ArticleEpilepsy & behavior : E&B2016
Serotonergic agents act on 5-HT
Article in Epilepsy & behavior : E&B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Serotonin Associated Mechanisms in Sudden Unexpected Death in Epilepsy: A Review.Revista de neurologia · 2026Review
- Respiratory dysfunction and fatal apnea during pilocarpine-induced status epilepticus.Epilepsia · 2026Article
- Challenges and future directions of SUDEP models.Lab animal · 2024Review
- Enhancing the action of serotonin by three different mechanisms prevents spontaneous seizure-induced mortality in Dravet mice.Epilepsia · 2024Article
- 5-HT receptors exert differential effects on seizure-induced respiratory arrest in DBA/1 mice.PloS one · 2024Article
- Review
- The mechanism of sudden unexpected death in epilepsy: A mini review.Frontiers in neurology · 2023Review
- Serotonin receptors in epilepsy: Novel treatment targets?Epilepsia open · 2022Review
- Adrenergic α2 receptors are implicated in seizure-induced respiratory arrest in DBA/1 mice.Life sciences · 2021Article
- An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies.International journal of molecular sciences · 2021Review
- Effect of fluoxetine on seizures in rats with high susceptibility to audiogenic stress.Journal of clinical and translational research · 2021Article
- Genistein, a Natural Isoflavone, Alleviates Seizure-Induced Respiratory Arrest in DBA/1 Mice.Frontiers in neurology · 2021Article
- Intraperitoneal injection of lipopolysaccharide prevents seizure-induced respiratory arrest in a DBA/1 mouse model of SUDEP.Epilepsia open · 2020Article
- Serotonin and sudden unexpected death in epilepsy.Experimental neurology · 2020Review
- Postictal serotonin levels are associated with peri-ictal apnea.Neurology · 2019Article
- The association of serotonin reuptake inhibitors and benzodiazepines with ictal central apnea.Epilepsy & behavior : E&B · 2019Article
- Impaired COTrends in neurosciences · 2019Review
- The ventrolateral medulla and medullary raphe in sudden unexpected death in epilepsy.Brain : a journal of neurology · 2018Article
- Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model.Neurobiology of disease · 2018Article
- The effect of atomoxetine, a selective norepinephrine reuptake inhibitor, on respiratory arrest and cardiorespiratory function in the DBA/1 mouse model of SUDEP.Epilepsy research · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Drugs that enhance the action of serotonin (5-hydroxytrypamine, 5-HT), including several selective serotonin reuptake inhibitors (SSRIs), reduce susceptibility to seizure-induced respiratory arrest (S-IRA) that leads to death in the DBA/1 mouse model of sudden unexpected death in epilepsy (SUDEP). However, it is not clear if specific 5-HT receptors are important in the action of these drugs and whether the brain is the major site of action of these agents in this SUDEP model. The current study examined the actions of agents that affect the 5-HT
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.