ArticleMicrobiologyOpen2017
Food to some, poison to others - honeybee royal jelly and its growth inhibiting effect on European Foulbrood bacteria.
Article in MicrobiologyOpen, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 73 citations in OpenAlex.
- Bacterial supplementation shapes honey bee gut microbiota and host metabolism under controlled and field conditions.mSystems · 2026Article
- Ectopic expression of structurally similar major royal jelly proteins reveals their distinct functions inJournal of Zhejiang University. Science. B · 2026Article
- Ecology and Pathogenicity for Honey Bee Brood of Recently Described Paenibacillus melissococcoides and Comparison With Paenibacillus dendritiformis, Paenibacillus thiaminolyticus.Environmental microbiology reports · 2025Article
- Evaluation of minimum inhibitory concentration and minimum bactericidal concentration of royal jelly againstJournal of conservative dentistry and endodontics · 2024Article
- Chemical Composition and Nutritional Value of Royal Jelly Samples Obtained from Honey Bee (Insects · 2024Article
- Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages.mSystems · 2024Article
- Influence of Honey bee Nutritive Jelly Type and Dilution on its Bactericidal Effect on Melissococcus plutonius, the Etiological Agent of European Foulbrood.Microbial ecology · 2023Article
- A high-throughput sequencing survey characterizing European foulbrood disease and Varroosis in honey bees.Scientific reports · 2023Article
- Detection and pH-Thermal Characterization of Proteinases Exclusive of Honeybee Worker-Fate Larvae (International journal of molecular sciences · 2022Article
- Royal Jelly as a Nutraceutical Natural Product with a Focus on Its Antibacterial Activity.Pharmaceutics · 2022Review
- Evaluating approved and alternative treatments against an oxytetracycline-resistant bacterium responsible for European foulbrood disease in honey bees.Scientific reports · 2022Article
- Lack of evidence for trans-generational immune priming against the honey bee pathogen Melissococcus plutonius.PloS one · 2022Article
- The Bioactive Compound Contents and Potential Protective Effects of Royal Jelly Protein Hydrolysates against DNA Oxidative Damage and LDL Oxidation.Antioxidants (Basel, Switzerland) · 2021Article
- Characterization ofCells · 2021Review
- Modification of the head proteome of nurse honeybees (Apis mellifera) exposed to field-relevant doses of pesticides.Scientific reports · 2020Article
- Towards Precision Nutrition: A Novel Concept Linking Phytochemicals, Immune Response and Honey Bee Health.Insects · 2019Review
- The rise and fall of major royal jelly proteins during a honeybee (Ecology and evolution · 2019Article
- Article
- pH-dependent stability of honey bee (Apis mellifera) major royal jelly proteins.Scientific reports · 2019Article
- Virulence of Melissococcus plutonius and secondary invaders associated with European foulbrood disease of the honey bee.MicrobiologyOpen · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Honeybee colonies (Apis mellifera) serve as attractive hosts for a variety of pathogens providing optimal temperatures, humidity, and an abundance of food. Thus, honeybees have to deal with pathogens throughout their lives and, even as larvae they are affected by severe brood diseases like the European Foulbrood caused by Melissococcus plutonius. Accordingly, it is highly adaptive that larval food jelly contains antibiotic compounds. However, although food jelly is primarily consumed by bee larvae, studies investigating the antibiotic effects of this jelly have largely concentrated on bacterial human diseases. In this study, we show that royal jelly fed to queen larvae and added to the jelly of drone and worker larvae, inhibits not only the growth of European Foulbrood-associated bacteria but also its causative agent M. plutonius. This effect is shown to be caused by the main protein (major royal jelly protein 1) of royal jelly.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.