ArticleDigestive diseases and sciences2016
Increased Proliferative Activity Accompanies the Local Inflammatory Response of Gastric Mucosa After Intragastric Balloon Insertion.
Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- A single-center experience of safety and effectiveness of adjustable intragastric balloon in patients with super obesity.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025Article
- Bone Densitometry and Fat Index after Sleeve and Subsleeve Gastrectomy in Animal Model.Advanced biomedical research · 2022Article
- Gastric perforation during second intragastric balloon treatment: a case report.AME case reports · 2022Article
- Gastric Balloon Implantation as Part of Morbid Adiposity Therapy Changes the Structure of the Stomach Wall.Visceral medicine · 2021Article
- Routine Intra-gastric Balloon Insertion in the Management of 'Super-Super-Obese' Patients: an Obituary?Obesity surgery · 2021Article
- Dysplastic urothelial changes accompany empagliflozin administration in urinary bladder of experimental diabetes.International journal of experimental pathology · 2019Article
- Impact of Intragastric Balloon Treatment on Adipokines, Cytokines, and Metabolic Profile in Obese Individuals.Obesity surgery · 2019Observational
- Can obesity-induced inflammation in skeletal muscle and intramuscular adipose tissue accurately detect liver fibrosis?Journal of musculoskeletal & neuronal interactions · 2018Article
- Correlation between testicular mast cell count and spermatogenic epithelium in non-obstructive azoospermia.International journal of experimental pathology · 2018Article
- Pioglitazone Induces Dysplastic Urothelial Changes in Urinary Bladder of Experimental Diabetes.Journal of microscopy and ultrastructureArticle
- Impaired Glucose Homeostasis Accompanies Cellular Changes in Endocrine Pancreas after Atorvastatin Administration.Journal of microscopy and ultrastructureArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimThe use of BioEnterics intragastric balloon (BIB) is progressively increasing, owing to the fact that morbid obesity becomes a global epidemic together with risks of bariatric surgery. Yet, the possible local BIB effect on gastric mucosa is not clearly elucidated. The aim of the current study was to assess the histological changes occurring in the gastric mucosa post-BIB insertion.
methodsGastric mucosa biopsy was obtained from 87 cases of morbid obesity both pre-BIB and 6 months post-BIB insertion to compare the local changes by histological and immunohistochemical analysis.
resultsAn inflammatory reaction was detected in the post-BIB mucosa which displayed a positive CD20, CD3 (p < 0.05), and the proliferation index (Ki67) increased significantly compared with that of the pre-BIB cases. The Ki67 index showed a significant positive correlation with CD20 and CD3 immunoexpression in the post-BIB gastric mucosae.
conclusionOur results demonstrated a possible increase in the gastric proliferative activity after BIB insertion accompanied with a remarkable local inflammatory reaction. Although these findings may be reactive and transient, endoscopic follow-up is recommended for early detection of further pathological changes.
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