ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017
Arterial stiffness shown by the cardio-ankle vascular index is an important contributor to optic nerve head microcirculation.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Evaluation of Microcirculation at the Optic Nerve Head in Eyes With Keratoconus.Investigative ophthalmology & visual science · 2026Article
- Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio-Vascular-Skeletal Muscle Coupling.Journal of clinical medicine · 2023Article
- Retinal Vessel Pulsatile Characteristics Associated With Vascular Stiffness Can Predict the Rate of Functional Progression in Glaucoma Suspects.Investigative ophthalmology & visual science · 2023Article
- Ankle-brachial index and ocular diseases in a Russian population.Eye (London, England) · 2022Article
- Characteristics of laterality in the optic nerve head microcirculation obtained by laser speckle flowgraphy in healthy subjects.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- Tooth Loss and Carotid Intima-Media Thickness in Relation to Functional Atherosclerosis: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Effects of aging and exercise habits on blood flow profile of the ocular circulation.PloS one · 2022Article
- Real-Time Evaluation of Regional Arterial Stiffening, Resistance, and Ocular Circulation During Systemic Administration of Adrenaline in White Rabbits.Translational vision science & technology · 2021Article
- Characterization of laser speckle flowgraphy pulse waveform parameters for the evaluation of the optic nerve head and retinal circulation.Scientific reports · 2021Article
- Longitudinal Testing of Retinal Blood Flow in a Mouse Model of Hypertension by Laser Speckle Flowgraphy.Translational vision science & technology · 2021Article
- Association between serum sodium level within normal range and handgrip strength in relation to hypertension status: a cross-sectional study.Scientific reports · 2021Article
- Ocular and Systemic Factors Affecting Laser Speckle Flowgraphy Measurements in the Optic Nerve Head.Translational vision science & technology · 2021Article
- Commentary: Cardio-ankle vascular index: The how and why for an ophthalmologist.Indian journal of ophthalmology · 2020Article
- Increased cardio-ankle vascular index values in patients with acute branch retinal vein occlusion.Indian journal of ophthalmology · 2020Article
- Influence of age and gender on the pulse waveform in optic nerve head circulation in healthy men and women.Scientific reports · 2019Article
- The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes.Journal of ophthalmology · 2019Article
- Relationship between Metabolic Syndrome and Ocular Microcirculation Shown by Laser Speckle Flowgraphy in a Hospital Setting Devoted to Sleep Apnea Syndrome Diagnostics.Journal of diabetes research · 2017Article
- Effects of water drinking test on ocular blood flow waveform parameters: A laser speckle flowgraphy study.PloS one · 2017Article
- Dynamic Alterations in Blood Flow in Glaucoma Measured with Laser Speckle Contrast Imaging.Ophthalmology. GlaucomaObservational
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
proposeThe purpose of this study was to determine whether there were significant correlations between the pulse waveform in the capillary area of the optic nerve head (ONH) microcirculation shown by laser speckle flowgraphy (LSFG) and parameters of the systemic condition, especially the cardio-ankle vascular index (CAVI).
methodWe studied 130 men (ages 60.5 ± 10.9 years) who visited the Vascular Function Section of the Department of Cardiovascular Center of Toho University Sakura Medical Center. We evaluated the skew and blowout time (BOT) - which are parameters of pulse waveform analyses - using LSFG in the capillary area of the ONH for each patient. The CAVI, the E/e' ratio as the measure of diastolic left ventricular function, and the mean intima-media thickness (IMT) were evaluated as systemic parameters. We performed a Pearson's correlation analysis and a multiple regression analysis to determine independent factors for skew and BOT.
resultsHeart rate, spherical refraction, and the CAVI (standard regression = 0.18, t = 2.61, p = 0.01) were revealed as factors contributing independently to the skew by multiple regression analysis. Heart rate, the CAVI (standard regression = -0.27, t = -3.92, p = 0.0002), the urinary albumin concentration, the mean IMT, spherical refraction, body mass index and pulse pressure were revealed as factors contributing independently to the BOT by multiple regression analysis.
conclusionThe CAVI was demonstrated to be an independent factor contributing to both skew and BOT in the capillary area of the ONH. Our findings clarified that large arterial function shown by the CAVI contributes to smooth hemodynamics of microcirculation, shown by LSFG.
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