ReviewBasic research in cardiology2016
From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research".
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Review in Basic research in cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
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Who cites it
30 citing papers in PubMed, 51 citations in OpenAlex.
- The study on the role of O-GlcNAcylation of SIRT3 in regulating mitochondrial oxidative stress during simulate myocardial ischemia-reperfusion.Scientific reports · 2024Article
- Identification and Validation of Glycosylation-Related Genes in Obesity and MASH: Insights from Human Liver Samples and a High-Fat Diet Mouse Model.Pharmacogenomics and personalized medicine · 2024Article
- Role of RIPK3‑CaMKII‑mPTP signaling pathway‑mediated necroptosis in cardiovascular diseases (Review).International journal of molecular medicine · 2023Review
- Article
- Emodin Regulates lncRNA XIST/miR-217 Axis to Protect Myocardial Ischemia-Reperfusion Injury.Oxidative medicine and cellular longevity · 2023Article
- Hypertrophic Preconditioning Attenuates Myocardial Ischaemia-Reperfusion Injury by Modulating SIRT3-SOD2-mROS-Dependent Autophagy.Cell proliferation · 2021Article
- Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction.Cardiovascular research · 2021Article
- Modulatory Effect of Myokines on Reactive Oxygen Species in Ischemia/Reperfusion.International journal of molecular sciences · 2020Review
- A Potential Involvement of Anandamide in the Modulation of HO/NOS Systems: Women, Menopause, and "Medical Cannabinoids".International journal of molecular sciences · 2020Article
- Tuscany Sangiovese grape juice imparts cardioprotection by regulating gene expression of cardioprotective C-type natriuretic peptide.European journal of nutrition · 2020Article
- Obesity subtypes, related biomarkers & heterogeneity.The Indian journal of medical research · 2020Review
- Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study.International journal of molecular sciences · 2019Article
- Involvement of Endothelin-1, HCellular and molecular neurobiology · 2019Article
- Role of Macrophages in Cardioprotection.International journal of molecular sciences · 2019Review
- Stem Cell Therapies in Cardiovascular Disease.Journal of cardiothoracic and vascular anesthesia · 2019Review
- The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology.Basic research in cardiology · 2018Article
- The Role of Platelets in Ischemic Conditioning.Conditioning medicine · 2018Article
- Responses of Endothelial Cells Towards Ischemic Conditioning Following Acute Myocardial Infarction.Conditioning medicine · 2018Article
- "Remote" myokine protects from pulmonary ischemia/reperfusion injury by a surprising "proximal" control mechanism.Annals of translational medicine · 2018Article
- Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.Journal of hypertension · 2018Article
Corrections and comments
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Authors and funding
39 authors at 20 institutions in 16 countries.
Hector A Cabrera-FuentesInstitute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany.
Julian AragonesResearch Unit, Hospital of Santa Cristina, Research Institute Princesa, Autonomous University of Madrid, Madrid, Spain.
Jürgen BernhagenDepartment of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Ludwig-Maximilians-Universität, Munich, Germany.
Andreas BoeningDepartment of Cardiovascular Surgery, Medical School, Justus-Liebig-University, Giessen, Germany.
William A BoisvertDepartment of Microbiology, Kazan Federal University, Kazan, Russian Federation.
Hans E BøtkerDepartment of Cardiology, Aarhus University Hospital, Skejby, Aarhus N, Denmark.
Heerajnarain BulluckCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, 8 College Road, Singapore, 169857, Singapore.
Stuart CookCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, 8 College Road, Singapore, 169857, Singapore.
Fabio Di LisaDepartment of Biomedical Sciences, University of Padova, Padua, Italy.
Felix B EngelExperimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nuremberg, Germany.
Bernd EngelmannInstitut für Laboratoriumsmedizin, Ludwig-Maximilians-Universität, Munich, Germany.
Fulvia FerrazziInstitute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nuremberg, Germany.
Péter FerdinandyDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary.
Alan FongDepartment of Cardiology, Sarawak Heart Centre, Sarawak, Malaysia.
Ingrid FlemingInstitute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, Frankfurt, Germany.
Erich GnaigerD. Swarovski Research Lab, Department of Visceral, Transplant Thoracic Surgery, Medical Univ Innsbruck, Innsbruck, Austria.
Sauri Hernández-ReséndizCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, 8 College Road, Singapore, 169857, Singapore.
Siavash Beikoghli KalkhoranThe Hatter Cardiovascular Institute, University College London, London, UK.
Moo Hyun KimDepartment of Cardiology, Dong-A University Hospital, Busan, Korea.
Sandrine LecourHatter Institute and MRC Inter-University Cape Heart Unit, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Elisa A LiehnInstitute for Molecular Cardiovascular Research, RWTH University Hospital, Aachen, Germany.
Michael S MarberDepartment of Cardiology, The Rayne Institute, St Thomas' Campus, King's College London, London, UK.
Manuel MayrThe James Black Centre, King's College, University of London, London, UK.
Tetsuji MiuraDepartment of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Sang-Bing OngCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, 8 College Road, Singapore, 169857, Singapore.
Karlheinz PeterBaker IDI Heart and Diabetes Institute, Melbourne, Australia.
Daniel SeddingDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Manvendra K SinghCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, 8 College Road, Singapore, 169857, Singapore.
M Saadeh SuleimanBristol Heart Institute, University of Bristol, Bristol Royal Infirmary, Bristol, UK.
Hans J SchnittlerInstitute of Anatomy and Vascular Biology, Westfalian-Wilhelms-University, Münster, Germany.
Rainer SchulzInstitute of Physiology, Justus-Liebig University, Giessen, Germany.
Winston ShimNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Daniel TelloResearch Unit, Hospital of Santa Cristina, Research Institute Princesa, Autonomous University of Madrid, Madrid, Spain.
Carl-Wilhelm VogelDepartment of Pathology, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA.
Malcolm WalkerThe Hatter Cardiovascular Institute, University College London, London, UK.
Qilong Oscar Yang LiResearch Unit, Hospital of Santa Cristina, Research Institute Princesa, Autonomous University of Madrid, Madrid, Spain.
Derek M YellonThe Hatter Cardiovascular Institute, University College London, London, UK.
Derek J HausenloyCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, 8 College Road, Singapore, 169857, Singapore. derek.hausenloy@duke-nus.edu.sg.
Klaus T PreissnerInstitute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany.
National Heart Centre Singapore · SGUniversity College London · GBKazan Federal University · RUFriedrich-Alexander-Universität Erlangen-Nürnberg · DEHospital Universitario Santa Cristina · ESJustus-Liebig-Universität Gießen · DEKing's College London · GBAarhus University Hospital · DKBaker Heart and Diabetes Institute · AUBristol Royal Infirmary · GBDong-A University Hospital · KRGoethe University Frankfurt · DEInnsbruck Medical University · ATLudwig-Maximilians-Universität München · DEMedizinische Hochschule Hannover · DEMunich Cluster for Systems Neurology · DENational University of Singapore · SGSapporo Medical University · JPSarawak Biodiversity Centre · MYSemmelweis University · HU
Funding
Anti-inflammatory Cytokines in AtherosclerosisR01HL075677 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI BOISVERT, WILLIAM A · 2005 to 2008
$1.6MRho kinase in immune-mediated atherosclerosisR01HL081863 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI BOISVERT, WILLIAM A · 2007 to 2010
$1.6MBritish Heart Foundation FS/13/2/29892British Heart Foundation SP/12/5/29574British Heart Foundation TG/15/1/31518Department of HealthMedical Research Council G1000737Medical Research Council MR/K002066/1NHLBI NIH HHS R01 HL075677NHLBI NIH HHS R01 HL081863
Abstract
In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients' cohorts, the influence of co-morbidities and medications, as well as the contribution of innate immune reactions in cardioprotection. Moreover, developmental or systems biology approaches bear great potential in systematically uncovering unexpected components involved in ischemia-reperfusion injury or heart regeneration. Based on the characterization of particular platelet integrins, mitochondrial redox-linked proteins, or lipid-diol compounds in cardiovascular diseases, their targeting by newly developed theranostics and technologies opens new avenues for diagnosis and therapy of myocardial infarction to improve the patients' outcome.
Indexed as
Cardiovascular DiseasesAnimalsCardiologyHumansTheranostic NanomedicineCardiomyocyte signaling pathwaysCardioprotectionCardiovascular diseaseCo-morbiditiesDrug targetingEndothelial permeabilityExtracellular RNA (eRNA)Heart regenerationInduced pluripotent stem cellsIschemia–reperfusion injuryLipid metabolismMicroRNAs (miRNAs)MitochondriaRemote ischemic conditioning
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.