ArticleDevelopment genes and evolution2017
Heat shock protein 83 plays pleiotropic roles in embryogenesis, longevity, and fecundity of the pea aphid Acyrthosiphon pisum.
Article in Development genes and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 59 citations in OpenAlex.
- Conditionally essential: A testis-enriched heat shock protein from fall armyworm safeguards fertility and survival under heat stress.Pest management science · 2026Article
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- De Novo Transcriptome Profiling of Mustard Aphid (Insects · 2024Article
- High and Low Temperatures Differentially Affect Survival, Reproduction, and Gene Transcription in Male and Female Moths ofInsects · 2023Article
- Identification and expression analysis of heat shock protein family genes of gall fly (Procecidochares utilis) under temperature stress.Cell stress & chaperones · 2023Article
- Exposure to heat stress leads to striking clone-specific nymph deformity in pea aphid.PloS one · 2023Article
- Heat stress tolerance in peas (Frontiers in plant science · 2022Review
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- Impact of Temperature on Survival Rate, Fecundity, and Feeding Behavior of Two Aphids,Insects · 2021Article
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- RNAi-Based Functional Genomics in Hemiptera.Insects · 2020Review
- Lysine Acetyltransferase p300/CBP Plays an Important Role in Reproduction, Embryogenesis and Longevity of the Pea AphidInsects · 2020Article
- Ovary Proteome Analysis Reveals RH36 Regulates Reproduction via Vitellin Uptake Mediated by HSP70 Protein in Hard Ticks.Frontiers in cellular and infection microbiology · 2020Article
- Identification and Functional Characterization of a Novel Insecticidal Decapeptide from the Myrmicine AntToxins · 2019Article
- Molecular characterization, tissue-specific expression, and RNA knockdown of the putative heat shock cognate 70 protein from Rhipicephalus haemaphysaloides.Parasitology research · 2019Article
- Proteomic Analysis of the Venom from the Ruby AntInsects · 2019Article
- RNA-Seq analysis of Polyrhachis vicina Roger and insights into the heat shock protein 90 and 70 families.Cell stress & chaperones · 2019Article
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4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat shock protein 83 (HSP83) is homologous to the chaperone HSP90. It has pleiotropic functions in Drosophila melanogaster, including the control of longevity and fecundity, and facilitates morphological evolution by buffering cryptic deleterious mutations in wild populations. In the pea aphid Acyrthosiphon pisum, HSP83 expression is moderately induced by bacterial infection but upregulated more strongly in response to heat stress and fungal infection. Stress-inducible heat shock proteins are of considerable evolutionary and ecological importance because they are known to buffer environmental variation and to influence fitness under non-optimal conditions. To investigate the functions of HSP83 in viviparous aphids, we used RNA interference to attenuate its expression and studied the impact on complex parameters. The RNA interference (RNAi)-mediated depletion of HSP83 expression in A. pisum reduced both longevity and fecundity, suggesting this chaperone has an evolutionarily conserved function in insects. Surprisingly, HSP83 depletion reduced the number of viviparous offspring while simultaneously increasing the number of premature nymphs developing in the ovaries, suggesting an unexpected role in aphid embryogenesis and eclosion. The present study indicates that reduced HSP83 expression in A. pisum reveals both functional similarities and differences compared with its reported roles in holometabolous insects. Its impact on aphid lifespan, fecundity, and embryogenesis suggests a function that determines their fitness. This could be achieved by targeting different client proteins, recruiting distinct co-chaperones or transposon activation.
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