Evidence map›Paper›PMID 27742906›Full record

ArticleThe oncologist2016

Eribulin in Male Patients With Breast Cancer: The First Report of Clinical Outcomes.

Francesco Giotta, Luigi Acito, Giampiero Candeloro, Pietro Del Medico, Gennaro Gadaleta-Caldarola, Guido Giordano, Rossana Gueli, Antonio Lugini, Valentina Magri, Marta Mandarà and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in The oncologist, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Inflammatory Breast Cancer in a 53-Year-Old Man.Advanced biomedical research · 2022
    Article
  8. Review
  9. Male breast cancer: a disease distinct from female breast cancer.Breast cancer research and treatment · 2019
    Review
  10. Breast cancer: Eribulin effective against male breast cancer.Nature reviews. Clinical oncology · 2017
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 2 countries.

Francesco GiottaOncologia Medica, Istituti di Ricovero e Cura a Carattere Scientifico, Istituto Tumori "Giovanni Paolo II," Bari, Italy francescogiotta@libero.it.
Luigi AcitoOncologia Medica, Ospedale A. Murri, Fermo, Italy.
Giampiero CandeloroU.O.S.D. Oncologia P.O. Avezzano, Avezzano, Italy.
Pietro Del MedicoOncologia, Ospedali Riuniti, Reggio Calabria, Italy.
Gennaro Gadaleta-CaldarolaDivision of Medical Oncology, "Mons. R. Dimiccoli" Hospital, Barletta, Italy.
Guido GiordanoOspedale Sacro Cuore di Gesú Fatebenefratelli, Benevento, Italy.
Rossana GueliOspedale di Circolo e Fondazione Macchi Varese, Varese, Italy.
Antonio LuginiColumbus Clinic, Rome, Italy.
Valentina MagriPoliclinico Umberto I, Rome, Italy.
Marta MandaràSan Bonifacio Hospital, Verona, Italy.
Giovanna MasciHumanitas Cancer Center, Rozzano, Italy.
Salvatore PiscontiSan Giuseppe Moscati, ALS Taranto, Italy.
Mirco PistelliOspedali Riuniti, Ancona, Italy.
Anna RizziPoliambulanza Brescia, Brescia, Italy.
Nello SalesiOspedale Civile di Latina, Latina, Italy.
Alessio SchironeDepartment of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Istituti di Ricovero e Cura a Carattere Scientifico, Meldola, Italy.
Giovanni ScognamiglioOspedale Valduce, Como, Italy.
Maria TedeschiOspedale Israelitico, Rome, Italy.
Patrizia ZucchinelliSan Raffaele Hospital, Milan, Italy.
Azienda Ospedaliera S.Giuseppe Moscati · ITAzienda Ospedaliero Universitaria Ospedali Riuniti · ITFondazione Poliambulanza Istituto Ospedaliero · ITHumanitas University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Tumori Bari · ITOspedale di Circolo e Fondazione Macchi · ITOspedale Israelitico · ITOspedale Valduce · ITOspedali Riuniti di Foggia · ITPoliclinico Umberto I · ITRadiation Oncology Institute · USVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence on the management and treatment of male breast cancer is scant. We report the analysis of a multicenter Italian series of patients with male breast cancer treated with eribulin. To our knowledge, this is the first report on the use or eribulin in this setting. PATIENTS AND

methodsPatients were retrospectively identified in 19 reference centers. All patients received eribulin treatment, according to the standard practice of each center. Data on the identified patients were collected using a standardized form and were then centrally reviewed by two experienced oncologists.

resultsA total of 23 patients (median age, 64 years; range, 42-80) were considered. The median age at the time of diagnosis of breast cancer was 57 years (range, 42-74). HER2 status was negative in 14 patients (61%), and 2 patients (9%) had triple-negative disease. The most common metastatic sites were the lung (

conclusionAlthough hampered by all the limitations of any retrospective case series, the results of the present study suggest, for the first time, the use of eribulin as therapy for male breast cancer. IMPLICATIONS FOR PRACTICE: Evidence on the management and treatment of male breast cancer is eagerly awaited. Although hampered by all the limitations of any retrospective case series, the results of the present study suggest, for the first time, the use of eribulin as therapy for male breast cancer.

Indexed as

Clinical practiceEribulinMale breast cancerTreatment

Identifiers

PMID27742906
PMCPMC5189626
OpenAlexW2529912157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.