Evidence map›Paper›PMID 27742887›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Magnetic resonance imaging of blood-brain barrier permeability in ischemic stroke using diffusion-weighted arterial spin labeling in rats.

Yash V Tiwari, Jianfei Lu, Qiang Shen, Bianca Cerqueira, Timothy Q Duong

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06322212 (Type 2 Diabetes Mellitus and Blood Brain Barrier Improvement - A Randomized Clinical Trial), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06322212 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Type 2 Diabetes Mellitus and Blood Brain Barrier Improvement - A Randomized Clinical Trial

TypeinterventionalSponsorUniversity of California, Los AngelesRan2024 to 2027Enrolled52ConditionsType2diabetesArmsThiamine, Placebo
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Simultaneous measurement of water transport across the blood-brain and blood-CSF barrier in the human brain with arterial spin labeling MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  5. Review
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  10. Article
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  12. Article
  13. Heterogeneous blood-brain barrier dysfunction in cerebral small vessel diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yash V Tiwari1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, USA.
Jianfei Lu1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, USA.
Qiang Shen1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, USA.
Bianca Cerqueira1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, USA.
Timothy Q Duong1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, USA.
The University of Texas Health Science Center at San Antonio · USThe University of Texas at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffusion-weighted arterial spin labeling magnetic resonance imaging has recently been proposed to quantify the rate of water exchange (K

Indexed as

Blood-Brain BarrierIschemic Attack, TransientAnimalsCapillary PermeabilityContrast MediaDiffusion Magnetic Resonance ImagingDisease Models, AnimalEvans BlueMalePerfusionRats, Sprague-DawleySpin LabelsContrast MediaEvans BlueSpin Labelsarterial spin labelingCerebral ischemiadynamic contrast-enhanced magnetic resonance imagingEvans bluehyperperfusionperfusion imagingratsvasogenic edema

Identifiers

PMID27742887
PMCPMC5536782
OpenAlexW2531608968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.