Evidence map›Paper›PMID 27742866›Full record

ArticleBioscience reports2016

Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA.

Benjamin W Arentson, Erin L Hayes, Weidong Zhu, Harkewal Singh, John J Tanner, Donald F Becker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Structural Biology of Proline Catabolic Enzymes.Antioxidants & redox signaling · 2019
    Review
  2. Role of Proline in Pathogen and Host Interactions.Antioxidants & redox signaling · 2019
    Review
  3. Article
  4. Article
  5. Structure, function, and mechanism of proline utilization A (PutA).Archives of biochemistry and biophysics · 2017
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Benjamin W ArentsonDepartment of Biochemistry, Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68588, U.S.A.
Erin L HayesDepartment of Biochemistry, Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68588, U.S.A.
Weidong ZhuDepartment of Biochemistry, Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68588, U.S.A.
Harkewal SinghDepartment of Chemistry, University of Missouri-Columbia, Columbia, MO 65211, U.S.A.
John J TannerDepartment of Biochemistry, University of Missouri-Columbia, Columbia, MO 65211, U.S.A.
Donald F BeckerDepartment of Biochemistry, Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68588, U.S.A. dbecker3@unl.edu.
University of Nebraska–Lincoln · USProtein Technologies (United Kingdom) · GBUniversity of Missouri · US

Funding

Redox Biology CenterP30GM103335 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2012 to 2016
$4.3M
Spectroelectrochemistry of the Novel PutA FlavoproteinR01GM061068 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2001 to 2015
$3.7M
NIGMS NIH HHS P30 GM103335NIGMS NIH HHS R01 GM061068
6 · The paper itself

Abstract

Proline utilization A (PutA) is a bifunctional flavoenzyme with proline dehydrogenase (PRODH) and Δ

Indexed as

Bacterial ProteinsChimeraDNA-Binding ProteinsEscherichia coliMembrane ProteinsProlineProline OxidaseProtein BindingProtein DomainsPyrrolesRhodobacter capsulatusBacterial Proteinsdelta-1-pyrroline-5-carboxylateDNA-Binding ProteinsMembrane ProteinsProlineProline OxidasePutA protein, BacteriaPyrrolesDNA bindingflavin enzymeproline metabolismsmall-angle X-ray scattering (SAXS)

Identifiers

PMID27742866
PMCPMC5293562
OpenAlexW2530336509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.