Evidence map›Paper›PMID 27742796›Full record

Observational studyHeart (British Cardiac Society)2017

Kidney function and appropriateness of device therapies in adults with implantable cardioverter defibrillators.

Nisha Bansal, Adam Szpiro, Frederick Masoudi, Robert T Greenlee, David H Smith, David J Magid, Jerry H Gurwitz, Kristi Reynolds, Grace H Tabada, Sue Hee Sung and 10 more

Open access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Heart (British Cardiac Society), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 1 country.

Nisha BansalDivision of Nephrology, Kidney Research Institute, University of Washington, Seattle, Washington, USA.
Adam SzpiroDepartment of Biostatistics, University of Washington, Seattle, Washington, USA.
Frederick MasoudiUniversity of Colorado Hospital, Aurora, Colorado, USA.
Robert T GreenleeMarshfield Clinic Research Foundation, Wisconsin, USA.
David H SmithKaiser Permanente Northwest Center for Health Research, Portland, Oregon, USA.
David J MagidKaiser Permanente Colorado Institute for Health Research, Oakland, California, USA.
Jerry H GurwitzMeyers Primary Care Institute, Worcester, Massachusetts, USA.
Kristi ReynoldsKaiser Permanente Southern California Department of Research and Evaluation, Pasadena, California, USA.
Grace H TabadaKaiser Permanente Northern California Division of Research, Oakland, California, USA.
Sue Hee SungKaiser Permanente Northern California Division of Research, Oakland, California, USA.
Ashveena DigheDivision of Nephrology, Kidney Research Institute, University of Washington, Seattle, Washington, USA.
Andrea Cassidy-BushrowHenry Ford Hospital, Detroit, Michigan, USA.
Romel Garcia-MontillaMarshfield Clinic Research Foundation, Wisconsin, USA.
Stephen HammillMayo Clinic, Rochester, Minnesota, USA.
John HayesMarshfield Clinic Research Foundation, Wisconsin, USA.
Alan KadishTouro College, New York, USA.
Param SharmaMarshfield Clinic Research Foundation, Wisconsin, USA.
Paul VarosyUniversity of Colorado Hospital, Aurora, Colorado, USA.
Humberto VidailletMarshfield Clinic Research Foundation, Wisconsin, USA.
Alan S GoKaiser Permanente Northern California Division of Research, Oakland, California, USA.
Kaiser Permanente · USMarshfield Clinic · USUniversity of Washington · USUniversity of Colorado Hospital · USHenry Ford Hospital · USKaiser Permanente Center for Health Research · USMayo Clinic · USTouro College · US

Funding

HMO Research Network Cardiovascular Research NetworkU19HL091179 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2007 to 2011
$8.7M
Blood Pressure in Advanced Chronic Kidney DiseaseK23DK088865 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA · 2010 to 2014
$848k
CVRN-Risk with ICD Placement and Outcomes in Kidney Disease (CVRN-RISK) StudyR56HL121069 · NHLBI · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA · 2014 to 2014
$786k
HHS HHSA290-2005-0033-I-TO8-WANHLBI NIH HHS R56 HL121069NHLBI NIH HHS U19 HL091179NIDDK NIH HHS K23 DK088865
6 · The paper itself

Abstract

objectivePatients with chronic kidney disease (CKD) have higher risk of sudden cardiac death; however, they may not receive implantable cardioverter defibrillators (ICDs), in part due to higher risk of complications. We evaluated whether CKD is associated with greater risk of device-delivered shocks/antitachycardia pacing (ATP) therapies among patients receiving a primary prevention ICD.

methodsWe studied participants in the observational Cardiovascular Research Network Longitudinal Study of Implantable Cardioverter Defibrillators. CKD was defined as estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m

resultsAmong 2161 participants, 1066 (49.3%) had CKD (eGFR 44±11 mL/min/1.73 m

conclusionsIn adults receiving a primary prevention ICD, mild-to-moderate CKD was not associated with the timing, burden or appropriateness of subsequent device therapy. Potential concern for inappropriate ICD-delivered therapies should not preclude ICDs among eligible patients with CKD.

Indexed as

Defibrillators, ImplantableAgedAged, 80 and overDeath, Sudden, CardiacElectric CountershockFemaleGlomerular Filtration RateHeart FailureHumansKidneyLongitudinal StudiesMaleMiddle AgedPrimary PreventionProsthesis DesignProsthesis Failure

Identifiers

PMID27742796
PMCPMC5558610
OpenAlexW2529892550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.