Evidence map›Paper›PMID 27742752›Full record

Trial reportClinical rehabilitation2017

Independent exercise for glottal incompetence to improve vocal problems and prevent aspiration pneumonia in the elderly: a randomized controlled trial.

Yoko Fujimaki, Koichi Tsunoda, Rika Kobayashi, Chong Tonghyo, Fujinobu Tanaka, Hiroyuki Kuroda, Tsutomu Numata, Toyota Ishii, Reiko Kuroda, Sawako Masuda and 26 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Voice Meets Swallowing: A Scoping Review of Therapeutic Connections.American journal of speech-language pathology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Voice Therapy in the Context of the COVID-19 Pandemic: Guidelines for Clinical Practice.Journal of voice : official journal of the Voice Foundation · 2021
    Review
  10. Terapia de voz en el contexto de la pandemia covid-19; recomendaciones para la práctica clínica.Journal of voice : official journal of the Voice Foundation · 2021
    Review
  11. Terapia Vocal No Contexto Da Pandemia Do Covid-19; Orientações Para A Prática Clínica.Journal of voice : official journal of the Voice Foundation · 2021
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 9 institutions in 1 country.

Yoko Fujimaki1 Department of Artificial Organs and Medical Device Creation, National Institute of Sensory Organs, Tokyo, Japan.
Koichi Tsunoda1 Department of Artificial Organs and Medical Device Creation, National Institute of Sensory Organs, Tokyo, Japan.
Rika Kobayashi1 Department of Artificial Organs and Medical Device Creation, National Institute of Sensory Organs, Tokyo, Japan.
Chong Tonghyo3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Fujinobu Tanaka4 Department of Otolaryngology, National Hospital Organization Nagasaki Medical Center, Tokyo, Japan.
Hiroyuki Kuroda5 Department of Otolaryngology, National Hospital Organization Kobe Medical Center, Tokyo, Japan.
Tsutomu Numata6 Miura ENT Clinic, Tokyo, Japan.
Toyota Ishii7 Department of Otolaryngology, Sagamihara National Hospital, Tokyo, Japan.
Reiko Kuroda8 Department of Otolaryngology, Hirosaki National Hospital, Tokyo, Japan.
Sawako Masuda9 Department of Otolaryngology, National Mie Hospital, Tokyo, Japan.
Sho Hashimoto10 Department of Otolaryngology, National Sendai Medical Center, Tokyo, Japan.
Hayato Misawa11 Department of Otolaryngology, National Hospital Organization Nagoya Medical Center, Tokyo, Japan.
Naoko Shindo12 Department of Rehabilitation, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Takahiro Mori3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Hiroko Mori3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Naoki Uchiyama3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Yuichirou Kamei3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Masashi Tanaka3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Hironobu Hamaya3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Shingo Funatsuki3 Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Satoko Usui9 Department of Otolaryngology, National Mie Hospital, Tokyo, Japan.
Ikuno Ito12 Department of Rehabilitation, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Kohei Hamada12 Department of Rehabilitation, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Akihito Shindo13 Department of Otolaryngology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Yutaka Tokumaru13 Department of Otolaryngology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Yoko Morita14 Department of Neurology National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Rumi Ueha2 Department of Otolaryngology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Takaharu Nito2 Department of Otolaryngology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Shu Kikuta2 Department of Otolaryngology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Sotaro Sekimoto1 Department of Artificial Organs and Medical Device Creation, National Institute of Sensory Organs, Tokyo, Japan.
Kenji Kondo2 Department of Otolaryngology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Takashi Sakamoto2 Department of Otolaryngology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Kenji Itoh1 Department of Artificial Organs and Medical Device Creation, National Institute of Sensory Organs, Tokyo, Japan.
Tatsuya Yamasoba2 Department of Otolaryngology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Sumio Matsumoto1 Department of Artificial Organs and Medical Device Creation, National Institute of Sensory Organs, Tokyo, Japan.
Research Group for Aspiration Pneumonia, National Hospital Organization, Japan
National Hospital Organization · JPTokyo Medical Center · JPThe University of Tokyo · JPTokyo National Hospital · JPNational Mie Hospital · JPHirosaki National Hospital · JPNagasaki Medical Center · JPNational Sagamihara Hospital · JPSendai Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the effect of a self-controlled vocal exercise in elderly people with glottal closure insufficiency.

designParallel-arm, individual randomized controlled trial.

methodsPatients who visited one of 10 medical centers under the National Hospital Organization group in Japan for the first time, aged 60 years or older, complaining of aspiration or hoarseness, and endoscopically confirmed to have glottal closure insufficiency owing to vocal cord atrophy, were enrolled in this study. They were randomly assigned to an intervention or a control group. The patients of the intervention group were given guidance and a DVD about a self-controlled vocal exercise. The maximum phonation time which is a measure of glottal closure was evaluated, and the number of patients who developed pneumonia during the six months was compared between the two groups.

resultsOf the 543 patients enrolled in this trial, 259 were allocated into the intervention group and 284 into the control; 60 of the intervention group and 75 of the control were not able to continue the trial. A total of 199 patients (age 73.9 ±7.25 years) in the intervention group and 209 (73.3 ±6.68 years) in the control completed the six-month trial. Intervention of the self-controlled vocal exercise extended the maximum phonation time significantly ( p < 0.001). There were two hospitalizations for pneumonia in the intervention group and 18 in the control group, representing a significant difference ( p < 0.001).

conclusionThe self-controlled vocal exercise allowed patients to achieve vocal cord adduction and improve glottal closure insufficiency, which reduced the rate of hospitalization for pneumonia significantly. CLINICAL TRIAL: gov Identifier-UMIN000015567.

Indexed as

AgedAged, 80 and overAge FactorsAgingDeglutition DisordersExerciseGlottisHumansJapanLaryngoscopyMiddle AgedPatient CompliancePneumonia, AspirationPrognosisRecovery of FunctionReference ValuesAgingaspiration pneumoniaglottal closure insufficiencyrandomized controlled trialself-controlled vocal exercise

Identifiers

PMID27742752
PMCPMC5524188
OpenAlexW2531218018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.