Evidence map›Paper›PMID 27742618›Full record

Observational studyJournal of the American Heart Association2016

Sex Differences in Financial Barriers and the Relationship to Recovery After Acute Myocardial Infarction.

Adam L Beckman, Emily M Bucholz, Weiwei Zhang, Xiao Xu, Rachel P Dreyer, Kelly M Strait, John A Spertus, Harlan M Krumholz, Erica S Spatz

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026
    Review
  3. Article
  4. Article
  5. Observational
  6. Stress and cardiovascular disease: an update.Nature reviews. Cardiology · 2024
    Review
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Social and gender determinants related to health inequities in a community in ArgentinaRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Acute myocardial infarction in young women: current perspectives.International journal of women's health · 2018
    Review
  20. Young Women With Acute Myocardial Infarction: Current Perspectives.Circulation. Cardiovascular quality and outcomes · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Adam L BeckmanYale College, New Haven, CT.
Emily M BucholzDepartment of Medicine, Boston Children's Hospital, Boston, MA.
Weiwei ZhangCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.
Xiao XuDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.
Rachel P DreyerCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT Emergency Medicine, Yale University School of Medicine, New Haven, CT.
Kelly M StraitCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.
John A SpertusMid-America Heart Institute, University of Missouri-Kansas City, Kansas City, MO.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT Robert Wood Johnson Foundation Clinical Scholars Program, Yale University School of Medicine, New Haven, CT Department of Health Policy and Management, Yale School of Public Health, New Haven, CT.
Erica S SpatzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT erica.spatz@yale.edu.
Yale New Haven Hospital · USYale University · USBoston Children's Hospital · USUniversity of Missouri–Kansas City · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Young Women With Acute Myocardial InfarctionR01HL081153 · NHLBI · YALE UNIVERSITY · PI KRUMHOLZ, HARLAN MARC · 2007 to 2012
$10.6M
Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
Yale-CORE Career Development Program in Patient-Centered Outcomes ResearchK12HS023000 · AHRQ · YALE UNIVERSITY · PI KRUMHOLZ, HARLAN MARC · 2014 to 2018
$3.4M
AHRQ HHS K12 HS023000NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL081153NHLBI NIH HHS U01 HL105270
6 · The paper itself

Abstract

backgroundFinancial barriers to health care are associated with worse outcomes following acute myocardial infarction (AMI). Yet, it is unknown whether the prevalence of financial barriers and their relationship with post-AMI outcomes vary by sex among young adults. METHODS AND

resultsWe assessed sex differences in patient-reported financial barriers among adults aged <55 years with AMI using data from the Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients study. We examined the prevalence of financial barriers and their association with health status 12 months post-AMI. Among 3437 patients, more women than men reported financial barriers to medications (22.3% vs 17.2%; P=0.001), but rates of financial barriers to services were similar (31.3% vs 28.9%; P=0.152). In multivariable linear regression models adjusting for baseline health, psychosocial status, and clinical characteristics, compared with no financial barriers, women and men with financial barriers to services and medications had worse mental functional status (Short Form-12 mental health score: mean difference [MD]=-3.28 and -3.35, respectively), greater depressive symptomatology (Patient Health Questionnaire-9: MD, 2.18 and 2.16), lower quality of life (Seattle Angina Questionnaire-Quality of Life: MD, -4.98 and -7.66), and higher perceived stress (Perceived Stress Score: MD, 3.76 and 3.90; all P<0.05). There was no interaction between sex and financial barriers.

conclusionsFinancial barriers to care are common in young patients with AMI and associated with worse health outcomes 1 year post-AMI. Whereas women experienced more financial barriers than men, the association did not vary by sex. These findings emphasize the importance of addressing financial barriers to recovery post-AMI in young adults.

Indexed as

Health Services AccessibilityIncomeMedication AdherenceMyocardial InfarctionRecovery of FunctionAdultAftercareDepressionDrug CostsFemaleHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisPatient Health Questionnaireepidemiologymyocardial infarctionrisk factorswomen

Identifiers

PMID27742618
PMCPMC5121496
OpenAlexW2531222119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.