Evidence map›Paper›PMID 27742146›Full record

ArticleAmerican journal of infection control2016

Timeline of health care-associated infections and pathogens after burn injuries.

David van Duin, Paula D Strassle, Lauren M DiBiase, Anne M Lachiewicz, William A Rutala, Timothy Eitas, Robert Maile, Hajime Kanamori, David J Weber, Bruce A Cairns and 2 more

Abstract read
In one paragraph

Article in American journal of infection control, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Managing skin infections in burn patients: principles and pitfalls.Current opinion in infectious diseases · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Epidemiology and timing of infectious complications from battlefield-related burn injuries.Burns : journal of the International Society for Burn Injuries · 2024
    Article
  12. Review
  13. Multidrug-Resistant Organisms: The Silent Plight of Burn Patients.Journal of burn care & research : official publication of the American Burn Association · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David van DuinDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC. Electronic address: david_vanduin@med.unc.edu.
Paula D StrassleDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC.
Lauren M DiBiaseHospital Epidemiology, University of North Carolina Health Care, Chapel Hill, NC.
Anne M LachiewiczDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC.
William A RutalaDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC; Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, NC.
Timothy EitasNorth Carolina Jaycee Burn Center, Chapel Hill, NC; Host Defense Discovery Performance Unit, Glaxosmithkline, Research Triangle Park, NC.
Robert MaileHost Defense Discovery Performance Unit, Glaxosmithkline, Research Triangle Park, NC.
Hajime KanamoriDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC; Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, NC.
David J WeberDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC; Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, NC.
Bruce A CairnsNorth Carolina Jaycee Burn Center, Chapel Hill, NC; Department of Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Sonia NapravnikDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC; Department of Epidemiology, University of North Carolina, Chapel Hill, NC.
Samuel W JonesNorth Carolina Jaycee Burn Center, Chapel Hill, NC; Department of Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
Innate Immune Dysfunction Following Burn Inhalation Injury in Humans.K08GM109106 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONES, SAMUEL WAYNE · 2014 to 2017
$784k
NCATS NIH HHS KL2 TR001109NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002489NIGMS NIH HHS K08 GM109106
6 · The paper itself

Abstract

backgroundInfections are an important cause of morbidity and mortality after burn injuries. Here, we describe the time line of infections and pathogens after burns.

methodsA retrospective study was performed in a large tertiary care burn center from 2004-2013. Analyses were performed on health care-associated infections (HAIs) meeting Centers for Disease Control and Prevention criteria and on all positive cultures. Incidence rates per 1,000 days were calculated for specific HAI categories and pathogens and across hospitalization time (week 1, weeks 2-3, and week ≥4).

resultsAmong 5,524 patients, the median burn size was 4% of total body surface area (interquartile range, 2%-10%). Of the patients, 7% developed an HAI, of whom 33% had >1 HAI episode. Gram-positive bacteria were isolated earlier, and gram-negative bacteria were isolated later during hospitalization. Of 1,788 bacterial isolates, 44% met criteria for multidrug resistance, and 23% met criteria for extensive drug resistance. Bacteria tended to become increasingly resistant to antibiotics as time from admission increased.

conclusionsWe observed differences in infection type, pathogen, and antibiotic-resistant bacterium risk across time of hospitalization. These results may guide infection prevention in various stages of the postburn admission.

Indexed as

AdultBacteriaBacterial InfectionsBurnsCross InfectionFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk AssessmentSodium FluorideTertiary Care CentersUrethaneSodium FluorideTimeLineUrethaneBloodstream infectionBurnHealth care–associated infectionIntensive care unitPneumoniaTiming

Identifiers

PMID27742146
PMCPMC5388443

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.