ReviewClinics in geriatric medicine2016
The Role of Opioid Analgesics in Geriatric Pain Management.
Review in Clinics in geriatric medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality Indicators for the Pharmacological Management of Chronic Non-Cancer Pain in Older Adult Patients: An Integrative Review.Journal of evaluation in clinical practice · 2025Pooled it
- The Median Effective Concentration (EC50) of Alfentanil Combined with Propofol Closed-Loop Targeted Infusion in Super-Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP).Drug design, development and therapy · 2025Trial
- Effects of different doses of alfentanil on cardiovascular response to rapid sequence intubation in elderly patients: a parallel-controlled randomized trial.BMC anesthesiology · 2024Trial
- Opioid Exposure Negatively Affects Antidepressant Response to Venlafaxine in Older Adults with Chronic Low Back Pain and Depression.Pain medicine (Malden, Mass.) · 2020Trial
- Tolerability of buprenorphine transdermal system in nursing home patients with advanced dementia: a randomized, placebo-controlled trial (DEP.PAIN.DEM).Clinical interventions in aging · 2018Trial
- Opioids to Treat Chronic Pain in the Older Adult: A Clinical Consensus to Guarantee Safety and Avoid Adverse Events.Drugs & aging · 2026Review
- Changes in primary care provider behaviors after a brief educational intervention about opioid prescribing in older adults.BMC primary care · 2026Article
- [Androgen receptor-targeted therapies - avoid clinically relevant interactions].Aktuelle Urologie · 2026Review
- Acute pain management in older adults presenting to the emergency department: a clinical review.Singapore medical journal · 2026Review
- Critical appraisal of "Healthcare resource utilization for VELYS® robotic-assisted solution compared to manual surgery for total knee arthroplasty".Journal of robotic surgery · 2025Article
- Healthcare resource utilization for VELYS™ robotic-assisted solution compared to manual surgery for total knee arthroplasty.Journal of robotic surgery · 2025Article
- Comprehensive Approaches to Pain Management in Postoperative Spinal Surgery Patients: Advanced Strategies and Future Directions.Neurology international · 2025Review
- Pharmacological Pain Treatment in Older Persons.Drugs & aging · 2024Review
- Nonopioid analgesic use in older patients admitted for orthopedic rehabilitation.PM & R : the journal of injury, function, and rehabilitation · 2024Article
- The associations of oxaliplatin-induced peripheral neuropathy, sociodemographic characteristics, and clinical characteristics with time to fall in older adults with colorectal cancer.American journal of epidemiology · 2024Article
- Prehospital analgesia in suspected hip fracture patients: adherence to national prehospital pain management guidelines.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Observational
- Adverse Events of the Long-Term Use of Opioids for Chronic Non-cancer Pain: A Narrative Review.Cureus · 2024Review
- Enhanced Recovery after Surgery and Endometrial Cancers: Results from an Initial Experience Focused on Elderly Patients.Cancers · 2023Article
- Opioid use in older orthopedic rehabilitation inpatients: a retrospective study.European journal of physical and rehabilitation medicine · 2023Observational
- Potential pharmacological confounders in the setting of death determined by neurologic criteria: a narrative review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
When possible, chronic noncancer pain (CNCP) in older adults should be managed by nonpharmacologic modalities in conjunction with nonopioid analgesics. If moderate-to-severe pain persists despite these approaches, however, nonparenteral opioids may be considered as adjunctive therapy. This article reviews the epidemiology of opioid use and their effectiveness for CNCP in older adults and summarizes important age-related changes in opioid pharmacokinetics and pharmacodynamics that increase the risks of adverse effects in the elderly. Finally, to assist clinicians with selecting appropriate therapy, the article concludes with an evidence-based approach to optimize opioid prescribing in older adults with CNCP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.