Evidence map›Paper›PMID 27741965›Full record

ReviewClinics in geriatric medicine2016

Pharmacotherapies in Geriatric Chronic Pain Management.

Zachary A Marcum, Nakia A Duncan, Una E Makris

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in geriatric medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Paracetamol: A Review of Guideline Recommendations.Journal of clinical medicine · 2021
    Review
  12. Review
  13. Article
  14. Musculoskeletal Pain in Older Adults: A Clinical Review.The Medical clinics of North America · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Zachary A MarcumDepartment of Pharmacy, University of Washington School of Pharmacy, 1959 Northeast Pacific Avenue, Box 357630, Seattle, WA 98195, USA.
Nakia A DuncanTexas Tech University Health Sciences Center School of Pharmacy, 4500 South Lancaster Street, Building 7, Room 215, Dallas, TX, USA.
Una E MakrisDivision of Rheumatic Diseases, Department of Internal Medicine, VA North Texas Health Care System, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9169, USA. Electronic address: una.makris@utsouthwestern.edu.
Texas Tech University Health Sciences Center · USThe University of Texas Southwestern Medical Center · USUniversity of Washington · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid, ELAINE WETHINGTON · 2003 to 2026
$15.2M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1KL2TR001103 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$4.0M
Reid Aging and Pain Research Training ProgramK24AG053462 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI REID, MANNEY CARRINGTON · 2016 to 2025
$1.8M
Restricting Back Pain in Community-Living Older Persons: A Mixed-Methods ApproachR03AG040653 · NIA · YALE UNIVERSITY · PI MAKRIS, UNA E. · 2011 to 2012
$166k
HSRD VA IK2 HX001916NCATS NIH HHS KL2 TR001103NCATS NIH HHS UL1 TR001105NIA NIH HHS K24 AG053462NIA NIH HHS P30 AG022845NIA NIH HHS P30 AG024827NIA NIH HHS R03 AG040653NIA NIH HHS T32 AG021885
6 · The paper itself

Abstract

Pharmacologic management of chronic pain in older adults is one component of the multimodal, interdisciplinary management of this complex condition. In this article, we summarize several of the key barriers to effective pharmacologic management in older adults and review the existing (albeit limited) evidence for its effectiveness and safety, especially in a medically complex population with multimorbidity. This review covers topical formulations, acetaminophen, oral nonsteroidal antiinflammatory drugs, and adjuvant therapies. The article concludes with a suggested approach to managing chronic pain in the older patient, incorporating goals and expectations for treatment as well as careful monitoring of medication adjustments.

Indexed as

AgedAnti-Inflammatory Agents, Non-SteroidalChronic PainDrug CombinationsHumansPain ManagementAnti-Inflammatory Agents, Non-SteroidalDrug CombinationsAdverse drug eventsChronic painMedicationOlder adultsPolypharmacy

Identifiers

PMID27741965
PMCPMC5123672
OpenAlexW2531244294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.