Evidence map›Paper›PMID 27741951›Full record

Observational studyParasites & vectors2016

Epidemiological and clinical profile of adult patients with Blastocystis sp. infection in Barcelona, Spain.

Fernando Salvador, Elena Sulleiro, Adrián Sánchez-Montalvá, Carmen Alonso, Javier Santos, Isabel Fuentes, Israel Molina

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Blastocystis, urticaria, and skin disorders: review of the current evidences.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Pooled it
  2. Foodborne concerns ofFood and waterborne parasitology · 2024
    Review
  3. Article
  4. Article
  5. Diversity ofMicroorganisms · 2022
    Article
  6. Detection and molecular identification ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  7. Biology · 2021
    Article
  8. Article
  9. Microorganisms · 2021
    Article
  10. Article
  11. Microscopic examination after concentration techniques forParasite epidemiology and control · 2020
    Article
  12. Molecular Diversity ofMicroorganisms · 2020
    Article
  13. Molecular Epidemiology and Risk Factors ofRisk management and healthcare policy · 2020
    Article
  14. Article
  15. Evaluation of risk factors associated to detection of Blastocystis sp. in fecal samples in population from Barcelona, Spain: a case-control study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  16. Viability Screen of LOPACAntimicrobial agents and chemotherapy · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Fernando SalvadorDepartment of Infectious Diseases, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, PROSICS Barcelona, Barcelona, Spain. fmsalvad@vhebron.net.
Elena SulleiroDepartment of Microbiology, Vall d'Hebron University Hospital, PROSICS Barcelona, Barcelona, Spain.
Adrián Sánchez-MontalváDepartment of Infectious Diseases, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, PROSICS Barcelona, Barcelona, Spain.
Carmen AlonsoGastroenterology Department, Vall d' Hebron Research Institute, Digestive Diseases Research Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Javier SantosGastroenterology Department, Vall d' Hebron Research Institute, Digestive Diseases Research Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
Isabel FuentesInstituto de Salud Carlos III, National Centre of Microbiology, Madrid, Spain.
Israel MolinaDepartment of Infectious Diseases, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, PROSICS Barcelona, Barcelona, Spain.
Universitat Autònoma de Barcelona · ESInstituto de Salud Carlos III · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlastocystis spp. are among the most frequently observed intestinal parasites in humans. Despite the discovery of Blastocystis approximately 100 years ago, limited information is available regarding its pathogenesis, genetic diversity, and available treatment options. The aim of this study was to describe the epidemiological and clinical characteristics of patients with Blastocystis sp. infections diagnosed at Vall d'Hebron University Hospital (Barcelona, Spain).

methodsA retrospective observational study was performed which included all adult patients who attended Vall d'Hebron University Hospital from February 2009 to March 2014 that had Blastocystis sp. detected in their stool.

resultsFour hundred eighteen patients were included, the median age was 36 (18-86) years and 236 (56.5 %) were men. Regarding patient symptoms, 234 (56 %) patients were completely asymptomatic, 92 (22 %) patients had symptoms, and 92 (22 %) patients had symptoms that could be attributed to other causes. Of the 92 patients with symptoms not attributable to other etiologies except for Blastocystis infection, the most frequent symptoms were diarrhea (61 patients, 66.3 %) and abdominal pain (34 patients, 37 %). Additionally, nine (9.8 %) patients had cutaneous manifestations. Thirty-one (7.4 %) patients received specific treatment for Blastocystis infection. The clinical response of treated patients was varied. Five patients experienced complete resolution of symptoms, 12 patients reported improvement of clinical symptoms, eight patients described no clinical improvement, and information was unavailable for six patients.

conclusionsBlastocystis infection was detected in 418 patients, most of them foreign-born. Although the vast majority of patients were asymptomatic, 22 % of patients had gastrointestinal symptoms or cutaneous manifestations in the absence of other causes. Despite the scarce information available, given the safety of antiparasitic treatment, and the percentage of patients who experienced resolution or improvement of symptoms, treatment should be considered in patients with chronic symptoms.

Indexed as

AdolescentAdultAgedAged, 80 and overAntiprotozoal AgentsAsymptomatic InfectionsBlastocystisBlastocystis InfectionsDiarrheaFecesFemaleGastrointestinal DiseasesHumansIntestinesMaleMetronidazoleAntiprotozoal AgentsMetronidazoleBlastocystisGastrointestinal symptomsIntestinal protozoaMetronidazole

Identifiers

PMID27741951
PMCPMC5064914
OpenAlexW2530328885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.