ArticleBMC pediatrics2016
Nasal carriage of common bacterial pathogens among healthy kindergarten children in Chaoshan region, southern China: a cross-sectional study.
Article in BMC pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The pharyngeal carriage of Haemophilus influenzae among healthy population in China: a systematic review and meta-analysis.BMC infectious diseases · 2019Pooled it
- [Analysis of the clustering ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Host-microbiome archetypes differentiate infection from pathogen carriage in the human lower airway.Nature communications · 2026Article
- The Rho GTPase signaling pathway modulatesFrontiers in immunology · 2026Article
- Respiratory pathogens detected in children aged <5 years hospitalized with severe respiratory illness, South Africa, 2017.Frontiers in pediatrics · 2025Article
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- Staphylococcal Resistance Patterns,International journal of molecular sciences · 2023Article
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- Genotypic and Phenotypic Characteristics ofPathogens (Basel, Switzerland) · 2022Article
- Co-carriage ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
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- Prevalence ofInterdisciplinary perspectives on infectious diseases · 2022Article
- Bacteria and viruses in the upper respiratory tract of Congolese children with radiologically confirmed pneumonia.BMC infectious diseases · 2021Article
- [Clustering and influencing factors ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Determinants of Staphylococcus aureus carriage in the developing infant nasal microbiome.Genome biology · 2020Article
- Molecular characteristics and antimicrobial susceptibility of Staphylococcus aureus among children with respiratory tract infections in southwest China.World journal of pediatrics : WJP · 2020Article
- How nasopharyngeal pneumococcal carriage evolved during and after a PCV13-to-PCV10 vaccination programme switch in Belgium, 2016 to 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
- Article
- Colonization rate of Streptococcus pneumoniae, its associated factors and antimicrobial susceptibility pattern among children attending kindergarten school in Hawassa, southern Ethiopia.BMC research notes · 2019Article
- Simultaneous Detection of Key Bacterial Pathogens Related to Pneumonia and Meningitis Using Multiplex PCR Coupled With Mass Spectrometry.Frontiers in cellular and infection microbiology · 2018Article
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5 authors.
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Abstract
backgroundNasal colonization with bacterial pathogens is associated with risk of invasive respiratory tract infections, but the related information for Chinese healthy children is scarce.
methodsThis cross-sectional study was conducted with healthy children from 6 kindergartens in the Chaoshan region, southern China during 2011-2012. Nasal swabs were examined for five common bacterial pathogens: Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, and Staphylococcus aureus.
resultsAmong 1,088 children enrolled, 79.6 % (866) were target-bacterial carriers, of which 34.4 % (298/866) were positive for ≥2 bacteria species. The most common pathogen in the bacterial carriers was M. catarrhalis (76.6 %), followed by S. pneumoniae (26.6 %), S. aureus (21.8 %), H. parainfluenzae (12.7 %), and H. influenzae (2.3 %). Multiple logistic regression analyses showed negative associations between age and the overall or multiple bacterial carriage, and between the father's education level and multiple bacterial carriage (all p < 0.05). Age was negatively associated with the carriage of M. catarrhalis and S. pneumoniae, and positively associated with the S. aureus carriage (all p < 0.0001).
conclusionsThis study shows high nasal carriage of common pathogenic bacteria and coexistence of multiple pathogens in healthy Chaoshan kindergarten children, with M. catarrhalis as the commonest colonizer. Increasing age of children and higher paternal education are associated with lower risk of bacterial carriage. Longitudinal follow-up studies would be helpful for better understanding the infection risk in bacterial pathogen carriers.
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