Evidence map›Paper›PMID 27741574›Full record

ArticleChemical research in toxicology2016

DNA Polymerase ν Rapidly Bypasses O

A S Prakasha Gowda, Thomas E Spratt

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Beyond the Lesion: Back to High Fidelity DNA Synthesis.Frontiers in molecular biosciences · 2021
    Review
  2. The roles of polymerases ν and θ in replicative bypass ofThe Journal of biological chemistry · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

A S Prakasha GowdaDepartment of Biochemistry and Molecular Biology, Penn State College of Medicine, Pennsylvania State University , Hershey, Pennsylvania 17033, United States.
Thomas E SprattDepartment of Biochemistry and Molecular Biology, Penn State College of Medicine, Pennsylvania State University , Hershey, Pennsylvania 17033, United States.

Funding

Genotoxicity and Repair of Tobacco-Specific Nitrosamine DNA AdductsR01ES021762 · NIEHS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SPRATT, THOMAS E · 2012 to 2022
$3.7M
NIEHS NIH HHS R01 ES021762
6 · The paper itself

Abstract

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a potent tobacco carcinogen that forms mutagenic DNA adducts including O

Indexed as

DeoxyguanosineDNA-Directed DNA PolymeraseEscherichia coli ProteinsKineticsThymidineDeoxyguanosineDNA-Directed DNA PolymeraseDNA polymerase V, E coliEscherichia coli ProteinsO(6)-methyl-2'-deoxyguanosineThymidine

Identifiers

PMID27741574
PMCPMC5673091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.