Evidence map›Paper›PMID 27741408›Full record

ReviewAnnual review of virology2016

The Strange, Expanding World of Animal Hepaciviruses.

Alex S Hartlage, John M Cullen, Amit Kapoor

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Two bovine hepacivirus genome sequences from U.S. cattle.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  17. Identification and epidemiology of a novelFrontiers in veterinary science · 2024
    Article
  18. Article
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Alex S HartlageCenter for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205; email: amit.kapoor@nationwidechildrens.org.
John M CullenNorth Carolina State University College of Veterinary Medicine, Raleigh, North Carolina 27606.
Amit KapoorCenter for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205; email: amit.kapoor@nationwidechildrens.org.
Nationwide Children's Hospital · USNorth Carolina State University · USThe Ohio State University · US

Funding

Novel viruses and viral dynamics in multiple transfusion recipientsR01HL119485 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2014 to 2018
$2.0M
Study of rodent HCV-GBV like virusesR21AI107631 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2014 to 2015
$472k
NHLBI NIH HHS R01 HL119485NIAID NIH HHS R21 AI107631
6 · The paper itself

Abstract

Hepaciviruses and pegiviruses constitute two closely related sister genera of the family Flaviviridae. In the past five years, the known phylogenetic diversity of the hepacivirus genera has absolutely exploded. What was once an isolated infection in humans (and possibly other primates) has now expanded to include horses, rodents, bats, colobus monkeys, cows, and, most recently, catsharks, shedding new light on the genetic diversity and host range of hepaciviruses. Interestingly, despite the identification of these many animal and primate hepaciviruses, the equine hepaciviruses remain the closest genetic relatives of the human hepaciviruses, providing an intriguing clue to the zoonotic source of hepatitis C virus. This review summarizes the significance of these studies and discusses current thinking about the origin and evolution of the animal hepaciviruses as well as their potential usage as surrogate models for the study of hepatitis C virus.

Indexed as

AnimalsCattleChiropteraColobusFlavivirusGB virus AGB virus CGenetic VariationGenome, ViralHepacivirusHepatitis CHorsesHost SpecificityHumansPestivirusSharksanimal modelshepatitis C virushepegiviruspegivirusviromevirus evolution

Identifiers

PMID27741408
PMCPMC5523456
OpenAlexW2370703697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.