Evidence map›Paper›PMID 27741289›Full record

ArticlePloS one2016

Impact of Reconstruction Algorithms on CT Radiomic Features of Pulmonary Tumors: Analysis of Intra- and Inter-Reader Variability and Inter-Reconstruction Algorithm Variability.

Hyungjin Kim, Chang Min Park, Myunghee Lee, Sang Joon Park, Yong Sub Song, Jong Hyuk Lee, Eui Jin Hwang, Jin Mo Goo

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In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  7. Deep Learning-Based Image Reconstruction in Musculoskeletal MRI.Journal of the Korean Society of Radiology · 2025
    Review
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyungjin KimDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Chang Min ParkDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Myunghee LeeDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Sang Joon ParkDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Yong Sub SongDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Jong Hyuk LeeDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Eui Jin HwangDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Jin Mo GooDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify the impact of reconstruction algorithms on CT radiomic features of pulmonary tumors and to reveal and compare the intra- and inter-reader and inter-reconstruction algorithm variability of each feature.

methodsForty-two patients (M:F = 19:23; mean age, 60.43±10.56 years) with 42 pulmonary tumors (22.56±8.51mm) underwent contrast-enhanced CT scans, which were reconstructed with filtered back projection and commercial iterative reconstruction algorithm (level 3 and 5). Two readers independently segmented the whole tumor volume. Fifteen radiomic features were extracted and compared among reconstruction algorithms. Intra- and inter-reader variability and inter-reconstruction algorithm variability were calculated using coefficients of variation (CVs) and then compared.

resultsAmong the 15 features, 5 first-order tumor intensity features and 4 gray level co-occurrence matrix (GLCM)-based features showed significant differences (p<0.05) among reconstruction algorithms. As for the variability, effective diameter, sphericity, entropy, and GLCM entropy were the most robust features (CV≤5%). Inter-reader variability was larger than intra-reader or inter-reconstruction algorithm variability in 9 features. However, for entropy, homogeneity, and 4 GLCM-based features, inter-reconstruction algorithm variability was significantly greater than inter-reader variability (p<0.013).

conclusionsMost of the radiomic features were significantly affected by the reconstruction algorithms. Inter-reconstruction algorithm variability was greater than inter-reader variability for entropy, homogeneity, and GLCM-based features.

Indexed as

AlgorithmsAgedFemaleHumansLung NeoplasmsMaleMiddle AgedRadiation DosageRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID27741289
PMCPMC5065199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.