Evidence map›Paper›PMID 27741216›Full record

Trial reportMedicine and science in sports and exercise2017

Effect of Resistance Training and Caloric Restriction on the Metabolic Syndrome.

Eve Normandin, Elizabeth Chmelo, Mary F Lyles, Anthony P Marsh, Barbara J Nicklas

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine and science in sports and exercise, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 59 citations in OpenAlex.

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  15. Article
  16. Aerobic Exercise and Metabolic Syndrome: The Role of Sympathetic Activity and the Redox System.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eve Normandin1Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC; and 2Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC.
Elizabeth Chmelo
Mary F Lyles
Anthony P Marsh
Barbara J Nicklas
Wake Forest University · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Loss of fat tissue and functional responses to exercise in older, obese adultsR01AG020583 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J · 2002 to 2013
$4.0M
NCATS NIH HHS UL1 TR001420NIA NIH HHS P30 AG021332NIA NIH HHS R01 AG020583
6 · The paper itself

Abstract

purposeThe prevalence of metabolic syndrome (MetS) is greatest in older obese adults, and effective evidence-based treatment strategies are lacking. This study determined the efficacy of adding caloric restriction (CR) for weight loss to resistance training (RT) on MetS and its individual components in older overweight and obese adults.

methodsWe performed a 5-month randomized controlled trial in 126 older (65-79 yr) overweight and obese (body mass index = 27-35 kg·m) men and women who were assigned to a progressive 3-d·wk moderate-intensity RT with (RT + CR) or without caloric restriction (RT). MetS components, according to the National Cholesterol Education Program Adult Treatment Panel III, were determined before and immediately after the interventions.

resultsBody mass decreased in RT + CR (-5.67% loss of initial mass) but was unchanged in RT (-0.15%). Compared with RT, RT + CR resulted in reduced VLDL cholesterol, triglycerides, and systolic and diastolic blood pressures (P between 0.000 and 0.013). The RT group showed no significant within-group changes in MetS criteria. Abdominal obesity, hypertension, the number of metabolic abnormalities and the presence of MetS significantly decreased with RT + CR. There were significant group differences for abdominal obesity, hypertension, and number of metabolic abnormalities.

conclusionRT + CR is an effective strategy for improving some of the metabolic abnormalities associated with MetS among older overweight and obese adults.

Indexed as

Caloric RestrictionResistance TrainingAgedBody Fat DistributionBody Mass IndexExercise TherapyFemaleHumansMaleMetabolic SyndromeObesityOverweightRisk FactorsRisk Reduction BehaviorWeight Loss

Identifiers

PMID27741216
PMCPMC5315658
OpenAlexW2531866667

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.