Evidence map›Paper›PMID 27741033›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2016

Implementation and Operational Research: Evolution of Couples' Voluntary Counseling and Testing for HIV in Rwanda: From Research to Public Health Practice.

Etienne Karita, Sabin Nsanzimana, Felix Ndagije, Kristin M Wall, Jeannine Mukamuyango, Placidie Mugwaneza, Eric Remera, Pratima L Raghunathan, Roger Bayingana, Kayitesi Kayitenkore and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

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  5. Antibiotic-resistantInternational journal of STD & AIDS · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Etienne Karita*Project San Francisco (PSF), Kigali, Rwanda; †Department of Pathology & Laboratory Medicine, Emory University School of Medicine, Atlanta, GA; ‡Rwanda Biomedical Center (RBC), Kigali, Rwanda; §US Centers for Disease Control and Prevention (CDC), Kigali, Rwanda; ‖Department of Epidemiology, School of Public Health, Emory University, Atlanta, GA; ¶US Centers for Disease Control and Prevention, Center for Global Health, Atlanta, GA; and #Department of Pathology & Laboratory Medicine, Emory University School of Medicine, Atlanta, GA.
Sabin Nsanzimana
Felix Ndagije
Kristin M Wall
Jeannine Mukamuyango
Placidie Mugwaneza
Eric Remera
Pratima L Raghunathan
Roger Bayingana
Kayitesi Kayitenkore
Brigitte Bekan-Homawoo
Amanda Tichacek
Susan Allen
Emory University · USRwanda Biomedical Center · RWCenter for Global Health · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
EMORY AIDS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW001042 · FIC · EMORY UNIVERSITY · PI DEL RIO, CARLOS · 1998 to 2013
$6.8M
Couples HIV Counseling &Testing in two African capitalsR01MH066767 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLEN, SUSAN A · 2002 to 2006
$6.1M
Family Planning Promotion in HIV Infected ZambiansR01HD040125 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLEN, SUSAN A. · 2001 to 2005
$4.2M
PROJECT SAN FRANCISCO CENTER OF EXCELLENCE FOR THE EXPANSION OF CHCT IN RWANDA ANU2GPS001839 · PS · EMORY UNIVERSITY · PI ALLEN, SUSAN A · 2009 to 2014
$2.6M
VCT with Primary and Concurrent Partners to Prevent HIV Transmission R01MH095503 · NIMH · EMORY UNIVERSITY · PI ALLEN, SUSAN A · 2011 to 2016
$2.5M
RAWANDA ZAMBIA HIV RESEARCH GROUP CENTER OF EXCELENCE FOR THE EXPANSION OF CHCT SU2GPS001904 · PS · EMORY UNIVERSITY · PI ALLEN, SUSAN · 2009 to 2014
$2.3M
IUD, implant, and condoms: sexual and perinatal HIV prevention in Rwandan couplesR01HD072659 · NICHD · EMORY UNIVERSITY · PI ALLEN, SUSAN A · 2012 to 2016
$1.8M
HETEROSEXUAL TRANSMISSION AND THE NATURAL HISTORY OF HIVR01AI023980 · NIAID · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI ALLEN, SUSAN A. · 1988 to 1996
–
FIC NIH HHS D43 TW001042NCHHSTP CDC HHS U2G PS001839NCHHSTP CDC HHS U2G PS001904NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI023980NICHD NIH HHS R01 HD040125NICHD NIH HHS R01 HD072659NIMH NIH HHS R01 MH066767NIMH NIH HHS R01 MH095503
6 · The paper itself

Abstract

backgroundCouples' voluntary HIV counseling and testing (CVCT) is a WHO-recommended intervention for prevention of heterosexual HIV transmission which very few African couples have received. We report the successful nationwide implementation of CVCT in Rwanda.

methodsFrom 1988 to 1994 in Rwanda, pregnant and postpartum women were tested for HIV and requested testing for their husbands. Partner testing was associated with more condom use and lower HIV and sexually transmitted infection rates, particularly among HIV-discordant couples. After the 1994 genocide, the research team continued to refine CVCT procedures in Zambia. These were reintroduced to Rwanda in 2001 and continually tested and improved. In 2003, the Government of Rwanda (GoR) established targets for partner testing among pregnant women, with the proportion rising from 16% in 2003 to 84% in 2008 as the prevention of mother-to-child transmission program expanded to >400 clinics. In 2009, the GoR adopted joint posttest counseling procedures, and in 2010 a quarterly follow-up program for discordant couples was established in government clinics with training and technical assistance. An estimated 80%-90% of Rwandan couples have now been jointly counseled and tested resulting in prevention of >70% of new HIV infections.

conclusionsRwanda is the first African country to have established CVCT as standard of care in antenatal care. More than 20 countries have sent providers to Rwanda for CVCT training. To duplicate Rwanda's success, training and technical assistance must be part of a coordinated effort to set national targets, timelines, indicators, and budgets. Governments, bilateral, and multilateral funding agencies must jointly prioritize CVCT for prevention of new HIV infections.

Indexed as

CounselingOperations ResearchPatient CompliancePublic Health PracticeVoluntary ProgramsFamily CharacteristicsFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMalePostnatal CarePractice Guidelines as TopicPregnancyPrenatal CareRwanda

Identifiers

PMID27741033
PMCPMC5367509
OpenAlexW2489594989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.