ReviewExercise and sport sciences reviews2017
The Intriguing Role of Histamine in Exercise Responses.
Review in Exercise and sport sciences reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Histamine-receptor blockade does not influence the heavy-severe domain boundary and time to task failure in the severe domain during cycling exercise in adults.Physiological reports · 2025Trial
- Histamine is a molecular transducer of adaptation to endurance exercise training in humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Trial
- Antidiabetic Properties of Histamine H1 Receptor Antagonists: A Systematic Review.Antioxidants (Basel, Switzerland) · 2026Review
- Use of Antihistamine Drugs in Colitis: A Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Article
- Evidence of histamine release in response to both aerobic and resistance exercise: histamine metabolites as biomarkers.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Histamine Intolerance Through a Functional Medicine Lens: A Systems-Based Review.Integrative medicine (Encinitas, Calif.) · 2026Article
- Remodeling of the Mouse Liver and Skeletal Muscle Metabolome in Response to Continuous Acute Exercise and Disruption of AMPK-Glycogen Interactions.Metabolites · 2026Article
- Multi-omic responses to acute exercise in abdominal subcutaneous adipose tissue of sedentary adults: findings from MoTrPAC.bioRxiv : the preprint server for biology · 2026Article
- Article
- Lactate in Anaphylaxis: 100 Years On.Sports medicine (Auckland, N.Z.) · 2025Review
- Neurodivergence, intersectionality, and eating disorders: a lived experience-led narrative review.Journal of eating disorders · 2024Review
- Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation.Frontiers in cardiovascular medicine · 2023Article
- A Systematic Dry-Needling Treatment to Support Recovery Posttraining for Division I Ice Hockey Athletes: An Exploration Case Series.Journal of athletic training · 2022Article
- Side Effects and Patient Tolerance with the Use of Blood Flow Restriction Training after ACL Reconstruction in Adolescents: A Pilot Study.International journal of sports physical therapy · 2022Article
- Characterizing Marathon-Induced Metabolic Changes UsingMetabolites · 2021Article
- Histamine, mast cell tryptase and post-exercise hypotension in healthy and collapsed marathon runners.European journal of applied physiology · 2021Article
- Histamine HScience advances · 2021Article
- Real Assessment of Maximum Oxygen Uptake as a Verification After an Incremental Test Versus Without a Test.Frontiers in physiology · 2021Article
- Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells.Frontiers in immunology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In humans, histamine is a molecular transducer of physical activity responses, and antihistamines modify more than 25% of the genes responding to exercise. Although the upstream signal that results in release of histamine within exercising skeletal muscle remains to be identified, it is likely a fundamental exercise response and not an allergic reaction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.