Evidence map›Paper›PMID 27740511›Full record

ArticleEnvironmental health perspectives2017

Sex-Specific Associations between Particulate Matter Exposure and Gene Expression in Independent Discovery and Validation Cohorts of Middle-Aged Men and Women.

Karen Vrijens, Ellen Winckelmans, Maria Tsamou, Willy Baeyens, Patrick De Boever, Danyel Jennen, Theo M de Kok, Elly Den Hond, Wouter Lefebvre, Michelle Plusquin and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. PMEnvironmental research · 2022
    Article
  8. Review
  9. Altered Gene Expression in Dioxin-Like and Non-Dioxin-Like PCB Exposed Peripheral Blood Mononuclear Cells.International journal of environmental research and public health · 2019
    Article
  10. Article
  11. Epidemiological study of PMInternational journal of chronic obstructive pulmonary disease · 2018
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 3 countries.

Karen VrijensCentre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium.
Ellen Winckelmans
Maria Tsamou
Willy Baeyens
Patrick De Boever
Danyel Jennen
Theo M de Kok
Elly Den Hond
Wouter Lefebvre
Michelle Plusquin
Hans Reynders
Greet Schoeters
Nicolas Van Larebeke
Charlotte Vanpoucke
Jos Kleinjans
Tim S Nawrot
Hasselt University · BEMaastricht University · NLFlemish Institute for Technological Research · BEBelgian Development Agency · BEFlemish Government · BEGhent University Hospital · BEProvincial Institute for Hygiene · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParticulate matter (PM) exposure leads to premature death, mainly due to respiratory and cardiovascular diseases.

objectivesIdentification of transcriptomic biomarkers of air pollution exposure and effect in a healthy adult population.

methodsMicroarray analyses were performed in 98 healthy volunteers (48 men, 50 women). The expression of eight sex-specific candidate biomarker genes (significantly associated with PM

resultsAverage long-term PM

conclusionsExpression of the sex-specific candidate genes identified in the discovery population predicted PM

Indexed as

Particulate MatterAir PollutionCardiovascular DiseasesEnvironmental ExposureFemaleGene ExpressionHumansMaleMiddle AgedModels, TheoreticalRespiratory Tract DiseasesSex FactorsParticulate Matter

Identifiers

PMID27740511
PMCPMC5381989
OpenAlexW2530156559

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.