Evidence map›Paper›PMID 27740470›Full record

ReviewIEEE transactions on bio-medical engineering2017

-Omic and Electronic Health Record Big Data Analytics for Precision Medicine.

Po-Yen Wu, Chih-Wen Cheng, Chanchala D Kaddi, Janani Venugopalan, Ryan Hoffman, May D Wang

Abstract readReview
In one paragraph

Review in IEEE transactions on bio-medical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Iterative Reservoir Computing Networks for Reconstructing Irregular Time Series.IEEE transactions on neural networks and learning systems · 2025
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  19. Robust extraction of pneumonia-associated clinical states from electronic health records.Proceedings of the National Academy of Sciences of the United States of America · 2024
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Po-Yen Wu
Chih-Wen Cheng
Chanchala D Kaddi
Janani Venugopalan
Ryan Hoffman
May D Wang

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Contrast-Enhanced and Image-Guided Surgery of Lung CancerR01CA163256 · NCI · EMORY UNIVERSITY · PI JO, HANJOONG, SINGHAL, SUNIL · 2011 to 2015
$6.5M
NCATS NIH HHS UL1 TR000454NCI NIH HHS R01 CA163256
6 · The paper itself

Abstract

objectiveRapid advances of high-throughput technologies and wide adoption of electronic health records (EHRs) have led to fast accumulation of -omic and EHR data. These voluminous complex data contain abundant information for precision medicine, and big data analytics can extract such knowledge to improve the quality of healthcare.

methodsIn this paper, we present -omic and EHR data characteristics, associated challenges, and data analytics including data preprocessing, mining, and modeling.

resultsTo demonstrate how big data analytics enables precision medicine, we provide two case studies, including identifying disease biomarkers from multi-omic data and incorporating -omic information into EHR.

conclusionBig data analytics is able to address -omic and EHR data challenges for paradigm shift toward precision medicine. SIGNIFICANCE: Big data analytics makes sense of -omic and EHR data to improve healthcare outcome. It has long lasting societal impact.

Indexed as

Databases, FactualElectronic Health RecordsGenomicsMedical InformaticsPrecision MedicineHumans

Identifiers

PMID27740470
PMCPMC5859562

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.