ArticleScientific reports2016
The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 73 citations in OpenAlex.
- Dietary marigold-derived lutein produces dose- and time-dependent egg yolk enrichment and coordinated hepatic-ovarian responses in laying hens.Poultry science · 2026Article
- Dietary Effects of Carotenoid-Biofortified Wheat on Feed Conversion and Tissue Antioxidant Concentrations in Broiler Chickens.Foods (Basel, Switzerland) · 2026Article
- Enriching Eggs Naturally: The Nutritional Power of Black Soldier Fly Whole Dry Larvae.Animals : an open access journal from MDPI · 2026Article
- Production Performance and Properties of Eggs from Hens Fed Diets Differing in Corn Grain Hardness, Vitamin A Supplementation Level, and Mineral Form.Foods (Basel, Switzerland) · 2026Article
- Enhanced lycopene fortification in eggs using poultry feed containing a carotenoid-oil preparation derived from metabolically engineered baker's yeast.Scientific reports · 2026Article
- Genomic signatures of environmental adaptation in Danzhou chickens.BMC genomics · 2026Article
- Egg-based nutrient delivery system: advances in omega-3, antioxidant, and micronutrient enrichment.Frontiers in nutrition · 2026Review
- Integrated Analysis of Carotenoid Metabolism, Lipid Profiles, and Gut Microbiota Reveals Associations Fundamental to Skin Pigmentation in Lingshan Chickens.Animals : an open access journal from MDPI · 2025Article
- Utilization of Wheat with Enhanced Carotenoid Levels and Various Fat Sources in Hen Diets.Animals : an open access journal from MDPI · 2025Article
- Effects of Astaxanthin-rich Dried Cell Powder fromThe journal of poultry science · 2025Article
- Blood carotenoids as a biomarker of intestinal functionality and performance in broiler chickens.Frontiers in physiology · 2025Article
- Comparative metabolomic analysis of spaghetti meat and wooden breast in broiler chickens: unveiling similarities and dissimilarities.Frontiers in physiology · 2024Article
- Carotenoid enrichment in eggs: From biochemistry perspective.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Review
- Variations inGenes · 2023Article
- Pathogenesis of Chicken Astrovirus Related Illnesses.Frontiers in veterinary science · 2022Review
- Safety Evaluation of Porcine Bile Acids in Laying Hens: Effects on Laying Performance, Egg Quality, Blood Parameters, Organ Indexes, and Intestinal Development.Frontiers in veterinary science · 2022Article
- Porcine bile acids promote the utilization of fat and vitamin A under low-fat diets.Frontiers in nutrition · 2022Article
- Carotenoid Cocktail Produced by An Antarctic SoilMicroorganisms · 2021Article
- Bio Discarded from Waste to Resource.Foods (Basel, Switzerland) · 2021Review
- Metabolic engineering of astaxanthin-rich maize and its use in the production of biofortified eggs.Plant biotechnology journal · 2021Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carotenoids are important dietary nutrients with health-promoting effects. The biofortification of staple foods with carotenoids provides an efficient delivery strategy but little is known about the fate and distribution of carotenoids supplied in this manner. The chicken provides a good model of human carotenoid metabolism so we supplemented the diets of laying hens using two biofortified maize varieties with distinct carotenoid profiles and compared the fate of the different carotenoids in terms of distribution in the feed, the hen's livers and the eggs. We found that after a period of depletion, pro-vitamin A (PVA) carotenoids were preferentially diverted to the liver and relatively depleted in the eggs, whereas other carotenoids were transported to the eggs even when the liver remained depleted. When retinol was included in the diet, it accumulated more in the eggs than the livers, whereas PVA carotenoids showed the opposite profile. Our data suggest that a transport nexus from the intestinal lumen to the eggs introduces bottlenecks that cause chemically-distinct classes of carotenoids to be partitioned in different ways. This nexus model will allow us to optimize animal feed and human diets to ensure that the health benefits of carotenoids are delivered in the most effective manner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.