Evidence map›Paper›PMID 27739426›Full record

ArticleNature communications2016

Boundaries steer the contraction of active gels.

Matthias Schuppler, Felix C Keber, Martin Kröger, Andreas R Bausch

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
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  6. Engineering filamentous myosins for optical control of contractility.bioRxiv : the preprint server for biology · 2025
    Article
  7. Motor-driven microtubule diffusion in a photobleached dynamical coordinate system.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Review
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  16. Article
  17. Friction patterns guide actin network contraction.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Matthias SchupplerDepartment of Physics, Cellular Biophysics E27, Technical University of Munich, Garching D-85748, Germany.
Felix C KeberDepartment of Physics, Cellular Biophysics E27, Technical University of Munich, Garching D-85748, Germany.
Martin KrögerDepartment of Materials, Polymer Physics, ETH Zurich, Zurich CH-8093, Switzerland.
Andreas R BauschDepartment of Physics, Cellular Biophysics E27, Technical University of Munich, Garching D-85748, Germany.
Technical University of Munich · DEETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells set up contractile actin arrays to drive various shape changes and to exert forces to their environment. To understand their assembly process, we present here a reconstituted contractile system, comprising F-actin and myosin II filaments, where we can control the local activation of myosin by light. By stimulating different symmetries, we show that the force balancing at the boundaries determine the shape changes as well as the dynamics of the global contraction. Spatially anisotropic attachment of initially isotropic networks leads to a self-organization of highly aligned contractile fibres, being reminiscent of the order formation in muscles or stress fibres. The observed shape changes and dynamics are fully recovered by a minimal physical model.

Indexed as

Actin CytoskeletonActinsActomyosinAlgorithmsAnimalsGelsLightModels, BiologicalMuscle ContractionMuscle, SkeletalMyosinsRabbitsActinsActomyosinGelsMyosins

Identifiers

PMID27739426
PMCPMC5067607
OpenAlexW2530651568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.