Evidence map›Paper›PMID 27738973›Full record

ArticleJournal of physiology and biochemistry2017

Octodon degus, a new model to study the agonist and plexus-induced response in the urinary bladder.

Francisco Eduardo Martin-Cano, Mercedes Caso-Agundez, Cristina Camello-Almaraz, Francisco Juan Santos, María Teresa Espin, Juan Antonio Madrid, Adolfo Diez-Perez, Pedro Javier Camello, Maria Jose Pozo

Abstract read
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In one paragraph

Article in Journal of physiology and biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Francisco Eduardo Martin-CanoDepartment of Physiology, Faculty of Nursing and Occupational Therapy, University of Extremadura, 10003, Caceres, Spain.
Mercedes Caso-AgundezDepartment of Physiology, Faculty of Nursing and Occupational Therapy, University of Extremadura, 10003, Caceres, Spain.
Cristina Camello-AlmarazDepartment of Physiology, Faculty of Nursing and Occupational Therapy, University of Extremadura, 10003, Caceres, Spain.
Francisco Juan SantosDigestive Surgery Service, "San Pedro de Alcantara" Hospital, 10003, Cáceres, Spain.
María Teresa EspinDigestive Surgery Service, "Infanta Cristina" Hospital, 06006, Badajoz, Spain.
Juan Antonio MadridChronobiology Laboratory, College of Biology, University of Murcia, IMIB-Arrixaca, 30100, Murcia, Spain.
Adolfo Diez-PerezMusculoskeletal research group, Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), ISCIII, IMIM (Hospital del Mar Research Institute), Barcelona, Spain.
Pedro Javier CamelloDepartment of Physiology, Faculty of Nursing and Occupational Therapy, University of Extremadura, 10003, Caceres, Spain.
Maria Jose PozoDepartment of Physiology, Faculty of Nursing and Occupational Therapy, University of Extremadura, 10003, Caceres, Spain. mjpozo@unex.es.
Universidad de Extremadura · ESHospital San Pedro de Alcántara · ESHospital Universitario Infanta Cristina · ESMunicipal Institute for Medical Research · ESUniversidad de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary bladder function consists in the storage and controlled voiding of urine. Translational studies require animal models that match human characteristics, such as Octodon degus, a diurnal rodent. This study aims to characterize the contractility of the detrusor muscle and the morphology and code of the vesical plexus from O. degus. Body temperature was measured by an intra-abdominal sensor, the contractility of detrusor strips was evaluated by isometric tension recording, and the vesical plexus was studied by electrical field stimulation (EFS) and immunofluorescence. The animals showed a diurnal chronotype as judged from core temperature. The myogenic contractile response of the detrusor muscle to increasing doses of KCl reached its maximum (31.04 mN/mm

Indexed as

Adenosine TriphosphateAnimalsBethanecholBody TemperatureCholinergic NeuronsElectric StimulationFluorescent Antibody Technique, IndirectGangliaHumansIn Vitro TechniquesMaleMuscarinic AgonistsMuscle ContractionMuscle, SmoothNatriuretic AgentsNitrergic NeuronsAdenosine TriphosphateBethanecholMuscarinic AgonistsNatriuretic AgentsPotassium ChlorideInnervation (MeSH terms)Muscle, smoothUrinary bladder

Identifiers

PMID27738973
OpenAlexW2530200384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.