Evidence map›Paper›PMID 27738878›Full record

Observational studyJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2016

Effect of Resected Gastric Volume on Ghrelin and GLP-1 Plasma Levels: a Prospective Study.

Federico Sista, Valentina Abruzzese, Marco Clementi, Sergio Carandina, Gianfranco Amicucci

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Federico SistaDipartimento di Scienze Cliniche Applicate e Biotecnologie (DISCAB)-Ospedale civile San Salvatore, University of L'Aquila, L'Aquila, Italy. silversista@gmail.com.ORCID 0000-0002-2149-0876
Valentina AbruzzeseDipartimento di Scienze Cliniche Applicate e Biotecnologie (DISCAB)-Ospedale civile San Salvatore, University of L'Aquila, L'Aquila, Italy.
Marco ClementiDipartimento di Scienze Cliniche Applicate e Biotecnologie (DISCAB)-Ospedale civile San Salvatore, University of L'Aquila, L'Aquila, Italy.
Sergio CarandinaService de Chirurgie Digestive-Hôpital Avicenne, Université Paris XIII, Bobigny, France.
Gianfranco AmicucciDipartimento di Scienze Cliniche Applicate e Biotecnologie (DISCAB)-Ospedale civile San Salvatore, University of L'Aquila, L'Aquila, Italy.
University of L'Aquila · ITUniversité Sorbonne Paris Nord · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe correlation between resected gastric volume (RGV) and neuro-humoral changes (ghrelin and GLP-1) after laparoscopic sleeve gastrectomy (LSG) and their effects on type 2 diabetes mellitus (T2DM) has been evaluated. MATERIALS: Ninety-eight patients were divided in two groups: RGV <1200 mL (group A: 53 pts) and RGV >1200 mL (group B: 45 pts). Insulin secretion (insulin area under the curve (AUC)), insulinogenic index (IGI) and insulin-resistance (homeostasis model assessment, HOMA

resultsA significant difference in T2DM resolution rate was observed after 6, 12 and 24 months in favour of RGV >1200 mL. Group B performed better than group A at the 3rd day and at the 6th, 12th and 24th months with regard to AUC, IGI and HOMA

conclusionGhrelin and GLP-1 changes play a role in the regulation of glucose metabolism during the 1st year after LSG. RGV influences ghrelin and GLP-1 plasma levels after LSG, with a significant improvement in the T2DM control.

Indexed as

GastrectomyAdultBariatric SurgeryDiabetes Mellitus, Type 2FemaleGhrelinGlucagon-Like Peptide 1Glucose Tolerance TestHumansInsulinInsulin ResistanceInsulin SecretionLaparoscopyMaleMiddle AgedObesity, MorbidGhrelinGlucagon-Like Peptide 1InsulinBariatric surgeryDiabetes mellitus type 2ObesitySleeve gastrectomyVolume resected

Identifiers

PMID27738878
OpenAlexW2530447381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.