Evidence map›Paper›PMID 27738775›Full record

ArticleEcoHealth2016

Investigating Rare Risk Factors for Nipah Virus in Bangladesh: 2001-2012.

Sonia T Hegde, Hossain M S Sazzad, M Jahangir Hossain, Mahbub-Ul Alam, Eben Kenah, Peter Daszak, Pierre Rollin, Mahmudur Rahman, Stephen P Luby, Emily S Gurley

Abstract read
In one paragraph

Article in EcoHealth, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prioritizing surveillance of Nipah virus in India.PLoS neglected tropical diseases · 2019
    Pooled it
  4. Review
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  7. Article
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  9. Nipah virus: a summary for clinicians.International journal of emergency medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Sonia T HegdeCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Hossain M S Sazzadicddr,b (formerly, International Center for Diarrheal Disease Research, Bangladesh), Centre for Communicable Diseases icddr,b, 68, Shaheed Tajuddin Ahmed Sharani, Mohakhali, Dhaka, 1212, Bangladesh.
M Jahangir Hossainicddr,b (formerly, International Center for Diarrheal Disease Research, Bangladesh), Centre for Communicable Diseases icddr,b, 68, Shaheed Tajuddin Ahmed Sharani, Mohakhali, Dhaka, 1212, Bangladesh.
Mahbub-Ul Alamicddr,b (formerly, International Center for Diarrheal Disease Research, Bangladesh), Centre for Communicable Diseases icddr,b, 68, Shaheed Tajuddin Ahmed Sharani, Mohakhali, Dhaka, 1212, Bangladesh.
Eben KenahUniversity of Florida, Florida, USA.
Peter DaszakEcoHealth Alliance, New York, USA.
Pierre RollinCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Mahmudur RahmanInstitute of Epidemiology, Disease Control and Research, Dhaka, Bangladesh.
Stephen P LubyCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Emily S Gurleyicddr,b (formerly, International Center for Diarrheal Disease Research, Bangladesh), Centre for Communicable Diseases icddr,b, 68, Shaheed Tajuddin Ahmed Sharani, Mohakhali, Dhaka, 1212, Bangladesh. egurley@icddrb.org.
Centers for Disease Control and Prevention · USInternational Centre for Diarrhoeal Disease Research · BDEcoHealth Alliance · USInstitute of Epidemiology, Disease Control and Research · BDMRC Unit the Gambia · GMUniversity of Florida · US

Funding

ADDRESSING EMERGING INFECTIOUS DISEASES IN BANGLADESHU01CI000628 · CI · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI LATRIELLE, SARA · 2009 to 2014
$21.1M
Intramural CDC HHS CC999999NCPDCID CDC HHS U01 CI000628
6 · The paper itself

Abstract

Human Nipah encephalitis outbreaks have been identified almost yearly in Bangladesh since 2001. Though raw date palm sap consumption and person-to-person contact are recognized as major transmission pathways, alternative pathways of transmission are plausible and may not have been identified due to limited statistical power in each outbreak. We conducted a risk factor analysis using all 157 cases and 632 controls surveyed in previous investigations during 2004-2012 to identify exposures independently associated with Nipah, since date palm sap was first asked about as an exposure in 2004. To further explore possible rare exposures, we also conducted in-depth interviews with all cases, or proxies, since 2001 that reported no exposure to date palm sap or contact with another case. Cases were 4.9 (95% 3.2-7.7) times more likely to consume raw date palm sap and 7.3 (95% 4.0-13.4) times more likely to have contact with a Nipah case than controls. In-depth interviews revealed that 39/182 (21%) of Nipah cases reporting neither date palm sap consumption nor contact with another case were misclassified. Prevention efforts should be focused on interventions to interrupt transmission through date palm sap consumption and person-to-person contact. Furthermore, pooling outbreak investigation data is a good method for assessing rare exposures.

Indexed as

Nipah VirusBangladeshDisease OutbreaksHenipavirus InfectionsHumansRisk FactorsBangladeshNipah viruspreventionrare exposuresrisk factorszoonoses

Identifiers

PMID27738775
PMCPMC5164848
OpenAlexW2531057247

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.