Evidence map›Paper›PMID 27738722›Full record

ArticleHerz2017

Diurnal characteristics of heart rate variability in patients with sarcoidosis.

Z Aktop, H Tanrıverdi, F Uygur, A İşleyen, B Kalaycı, Y C Gursoy, T Karabağ, M Aydın, I Akpınar

Abstract read
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In one paragraph

Article in Herz, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Association of non-linear dynamics of heart rate variability with all-cause mortality in patients with sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Z AktopFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey. dr.ziyaeddin@outlook.com.ORCID http://orcid.org/0000-0001-5034-298X
H TanrıverdiFaculty of Medicine, Department of Pulmonary Medicine, Bülent Ecevit University, Zonguldak, Turkey.
F UygurFaculty of Medicine, Department of Pulmonary Medicine, Bülent Ecevit University, Zonguldak, Turkey.
A İşleyenFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey.
B KalaycıFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey.
Y C GursoyFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey.
T KarabağFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey.
M AydınFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey.
I AkpınarFaculty of Medicine, Department of Cardiology, Bülent Ecevit University, 67600, Kozlu/Zonguldak, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate autonomic nervous system function by measuring heart rate variability (HRV) in patients with sarcoidosis without known cardiac manifestations. PATIENTS AND

methodsThe study comprised 61 participants, including 31 patients with sarcoidosis without known cardiac manifestations and 30 healthy volunteers. All participants underwent echocardiographic examination, 12-channel electrocardiography (ECG), and 24-h Holter monitoring. HRV parameters were determined and compared between the groups.

resultsThere were no differences between groups with regard to age, body mass index, systolic and diastolic blood pressure, or heart rate at the time of admission. In the time domain analyses, the 24-h, daytime, and night-time standard deviations of all normal-to-normal R‑R interval (SDNN) values were significantly lower in patients with sarcoidosis than those in the controls. The frequency domain analyses showed that 24-h and daytime low-frequency (LF) values, 24-h, daytime, and night-time high-frequency (HF) values were significantly lower in the patient group compared with the control group, whereas the night-time LF/HF ratio was significantly higher.

conclusionAlthough Holter ECG is not a diagnostic tool for cardiac sarcoidosis, the HRV parameters, especially the night-time LF/HF values, may demonstrate increased sympathetic activation in patients with sarcoidosis.

Indexed as

AdultAutonomic Nervous SystemBlood PressureCardiomyopathiesCircadian RhythmEchocardiographyElectrocardiographyElectrocardiography, AmbulatoryFemaleHeart RateHumansMaleMiddle AgedReference ValuesSarcoidosisSarcoidosis, PulmonaryAutonomic dysfunctionDiurnal rhythmHeart rate variabilityHolter monitoringSarcoidosis

Identifiers

PMID27738722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.