Evidence map›Paper›PMID 27738647›Full record

ArticleNPJ schizophrenia2016

Alterations in the hippocampus and thalamus in individuals at high risk for psychosis.

Fabienne Harrisberger, Roman Buechler, Renata Smieskova, Claudia Lenz, Anna Walter, Laura Egloff, Kerstin Bendfeldt, Andor E Simon, Diana Wotruba, Anastasia Theodoridou and 5 more

Abstract read
In one paragraph

Article in NPJ schizophrenia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Copy Number Variations and Schizophrenia.Molecular neurobiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fabienne HarrisbergerDepartment of Psychiatry, University of Basel , Basel, Switzerland.
Roman BuechlerThe Zurich Program for Sustainable Development of Mental Health Services, Psychiatric Hospital, University of Zurich , Zurich, Switzerland.
Renata SmieskovaDepartment of Psychiatry, University of Basel, Basel, Switzerland; Medical Image Analysis Centre, University of Basel, Basel, Switzerland.
Claudia LenzDepartment of Psychiatry, University of Basel , Basel, Switzerland.
Anna WalterDepartment of Psychiatry, University of Basel , Basel, Switzerland.
Laura EgloffDepartment of Psychiatry, University of Basel , Basel, Switzerland.
Kerstin BendfeldtMedical Image Analysis Centre, University of Basel , Basel, Switzerland.
Andor E SimonSpecialized Early Psychosis Outpatient Service for Adolescents and Young Adults, Department of Psychiatry , Bruderholz, Switzerland.
Diana WotrubaThe Zurich Program for Sustainable Development of Mental Health Services, Psychiatric Hospital, University of Zurich , Zurich, Switzerland.
Anastasia TheodoridouThe Zurich Program for Sustainable Development of Mental Health Services, Psychiatric Hospital, University of Zurich , Zurich, Switzerland.
Wulf RösslerThe Zurich Program for Sustainable Development of Mental Health Services, Psychiatric Hospital, University of Zurich , Zurich, Switzerland.
Anita Riecher-RösslerDepartment of Psychiatry, University of Basel , Basel, Switzerland.
Undine E LangDepartment of Psychiatry, University of Basel , Basel, Switzerland.
Karsten HeekerenThe Zurich Program for Sustainable Development of Mental Health Services, Psychiatric Hospital, University of Zurich , Zurich, Switzerland.
Stefan BorgwardtDepartment of Psychiatry, University of Basel, Basel, Switzerland; Medical Image Analysis Centre, University of Basel, Basel, Switzerland; Department of Psychosis Studies, King's College London, Institute of Psychiatry Psychology and Neuroscience, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduction in hippocampal volume is a hallmark of schizophrenia and already present in the clinical high-risk state. Nevertheless, other subcortical structures, such as the thalamus, amygdala and pallidum can differentiate schizophrenia patients from controls. We studied the role of hippocampal and subcortical structures in clinical high-risk individuals from two cohorts. High-resolution T

Identifiers

PMID27738647
PMCPMC5040554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.