Evidence map›Paper›PMID 27738435›Full record

ReviewStem cells international2016

Vascular Transdifferentiation in the CNS: A Focus on Neural and Glioblastoma Stem-Like Cells.

Sophie Guelfi, Hugues Duffau, Luc Bauchet, Bernard Rothhut, Jean-Philippe Hugnot

Open access · goldAbstract readReview
In one paragraph

Review in Stem cells international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. Review
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  11. Delivering Therapeutics to Glioblastoma: Overcoming Biological Constraints.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Article
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  15. Review
  16. Review
  17. Review
  18. Article
  19. CUX1 Facilitates the Development of Oncogenic PropertiesFrontiers in molecular biosciences · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sophie GuelfiINSERM U1051, Institut des Neurosciences de Montpellier, Hôpital St Eloi, 80 Avenue Augustin Fliche, 34091 Montpellier Cedex 05, France; Université Montpellier 2, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France.ORCID 0000-0002-3579-4969
Hugues DuffauINSERM U1051, Institut des Neurosciences de Montpellier, Hôpital St Eloi, 80 Avenue Augustin Fliche, 34091 Montpellier Cedex 05, France; CHU Montpellier, Hôpital Gui de Chauliac, 80 Avenue Augustin Fliche, 34295 Montpellier, France.ORCID 0000-0002-6558-2342
Luc BauchetINSERM U1051, Institut des Neurosciences de Montpellier, Hôpital St Eloi, 80 Avenue Augustin Fliche, 34091 Montpellier Cedex 05, France; CHU Montpellier, Hôpital Gui de Chauliac, 80 Avenue Augustin Fliche, 34295 Montpellier, France.
Bernard RothhutINSERM U1051, Institut des Neurosciences de Montpellier, Hôpital St Eloi, 80 Avenue Augustin Fliche, 34091 Montpellier Cedex 05, France.
Jean-Philippe HugnotINSERM U1051, Institut des Neurosciences de Montpellier, Hôpital St Eloi, 80 Avenue Augustin Fliche, 34091 Montpellier Cedex 05, France; Université Montpellier 2, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastomas are devastating and extensively vascularized brain tumors from which glioblastoma stem-like cells (GSCs) have been isolated by many groups. These cells have a high tumorigenic potential and the capacity to generate heterogeneous phenotypes. There is growing evidence to support the possibility that these cells are derived from the accumulation of mutations in adult neural stem cells (NSCs) as well as in oligodendrocyte progenitors. It was recently reported that GSCs could transdifferentiate into endothelial-like and pericyte-like cells both

Identifiers

PMID27738435
PMCPMC5055959
OpenAlexW2522388051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.