Evidence map›Paper›PMID 27737875›Full record

ArticleJournal of the American Heart Association2016

Using Large-Scale Linkage Data to Evaluate the Effectiveness of a National Educational Program on Antithrombotic Prescribing and Associated Stroke Prevention in Primary Care.

Zhixin Liu, Rachael Moorin, John Worthington, Geoffrey Tofler, Mark Bartlett, Rabia Khan, Yeqin Zuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. NPS MedicineWise: 20 years of change.Journal of pharmaceutical policy and practice · 2018
    Article
  6. Long-term morbidity and mortality in patients without early complications after stroke or transient ischemic attack.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Zhixin LiuNPS MedicineWise, Sydney, New South Wales, Australia Zhixin.liu@nps.org.au.
Rachael MoorinSchool of Public Health, Curtin University, Perth, Western Australia, Australia.
John WorthingtonIngham Institute, South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
Geoffrey ToflerRoyal North Shore Hospital, University of Sydney, New South Wales, Australia.
Mark BartlettSax Institute, Sydney, New South Wales, Australia.
Rabia KhanNPS MedicineWise, Sydney, New South Wales, Australia.
Yeqin ZuoNPS MedicineWise, Sydney, New South Wales, Australia.
Curtin University · AUIngham Institute · AUSax Institute · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe National Prescribing Service (NPS) MedicineWise Stroke Prevention Program, which was implemented nationally in 2009-2010 in Australia, sought to improve antithrombotic prescribing in stroke prevention using dedicated interventions that target general practitioners. This study evaluated the impact of the NPS MedicineWise Stroke Prevention Program on antithrombotic prescribing and primary stroke hospitalizations. METHOD AND

resultsThis population-based time series study used administrative health data linked to 45 and Up Study participants with a high risk of cardiovascular disease (CVD) to assess the possible impact of the NPS MedicineWise program on first-time aspirin prescriptions and primary stroke-related hospitalizations. Time series analysis showed that the NPS MedicineWise program was significantly associated with increased first-time prescribing of aspirin (P=0.03) and decreased hospitalizations for primary ischemic stroke (P=0.03) in the at-risk study population (n=90 023). First-time aspirin prescription was correlated with a reduction in the rate of hospitalization for primary stroke (P=0.02). Following intervention, the number of first-time aspirin prescriptions increased by 19.8% (95% confidence interval, 1.6-38.0), while the number of first-time stroke hospitalizations decreased by 17.3% (95% confidence interval, 1.8-30.0).

conclusionsConsistent with NPS MedicineWise program messages for the high-risk CVD population, the NPS MedicineWise Stroke Prevention Program (2009) was associated with increased initiation of aspirin and a reduced rate of hospitalization for primary stroke. The findings suggest that the provision of evidence-based multifaceted large-scale educational programs in primary care can be effective in changing prescriber behavior and positively impacting patient health outcomes.

Indexed as

Practice Patterns, Physicians'Primary Health CareQuality ImprovementAgedAspirinCardiovascular DiseasesFemaleGeneral PractitionersHumansInformation Storage and RetrievalMaleMiddle AgedPlatelet Aggregation InhibitorsPrimary PreventionRisk AssessmentStrokeAspirinPlatelet Aggregation Inhibitorsantithrombotichealth outcomespreventionprimary carestroke

Identifiers

PMID27737875
PMCPMC5121477
OpenAlexW2530711016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.