ArticleEnvironmental science & technology2016
Newly Identified DDT-Related Compounds Accumulating in Southern California Bottlenose Dolphins.
Article in Environmental science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 60 citations in OpenAlex.
- Nontargeted Screening in Environmental Monitoring Programs: An Update.Advances in experimental medicine and biology · 2026Review
- Extremophile hotspots linked to containerized industrial waste dumping in a deep-sea basin.PNAS nexus · 2025Article
- The persistent DDT footprint of ocean disposal, and ecological controls on bioaccumulation in fishes.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Reproductive toxicity of DDT in the Japanese medaka fish model: Revisiting the impacts of DDT+ on female reproductive health.Chemosphere · 2024Review
- Disentangling the History of Deep Ocean Disposal for DDT and Other Industrial Waste Off Southern California.Environmental science & technology · 2024Article
- Systemic Erysipelas Outbreak among Free-Ranging Bottlenose Dolphins, San Diego, California, USA, 2022.Emerging infectious diseases · 2023Article
- Development of a Dynamic Network Model to Identify Temporal Patterns of Structural Malformations in Zebrafish Embryos Exposed to a Model Toxicant, Tris(4-chlorophenyl)methanol.Journal of xenobiotics · 2023Article
- Tattoo Skin Disease in Cetacea: A Review, with New Cases for the Northeast Pacific.Animals : an open access journal from MDPI · 2022Review
- The ecotoxicological contaminant tris(4-chlorophenyl)methanol (TCPMOH) impacts embryonic development in zebrafish (Danio rerio).Aquatic toxicology (Amsterdam, Netherlands) · 2021Article
- Demographic Assessment of Mono(2-ethylhexyl) Phthalate (MEHP) and Monoethyl Phthalate (MEP) Concentrations in Common Bottlenose Dolphins (GeoHealth · 2021Article
- Non-targeted screening workflows for gas chromatography-high-resolution mass spectrometry analysis and identification of biomagnifying contaminants in biota samples.Analytical and bioanalytical chemistry · 2021Article
- Article
- Apex marine predators and ocean health: Proactive screening of halogenated organic contaminants reveals ecosystem indicator species.Chemosphere · 2019Article
- Transformation Products of Organic Contaminants and Residues-Overview of Current Simulation Methods.Molecules (Basel, Switzerland) · 2019Review
- Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum CaEnvironmental science & technology · 2018Article
- Comprehensive Screening Links Halogenated Organic Compounds with Testosterone Levels in Male Delphinus delphis from the Southern California Bight.Environmental science & technology · 2018Article
- Synthesis of the DDT metabolite 2,4-dichloro-1-[2-chloro-1-(4-chlorophenyl)ethenyl]benzene (o-Cl-DDMU) and its detection in abiotic and biotic samples.Environmental science and pollution research international · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
Nontargeted GC×GC-TOF/MS analysis of blubber from 8 common bottlenose dolphins (Tursiops truncatus) inhabiting the Southern California Bight was performed to identify novel, bioaccumulative DDT-related compounds and to determine their abundance relative to the commonly studied DDT-related compounds. We identified 45 bioaccumulative DDT-related compounds of which the majority (80%) is not typically monitored in environmental media. Identified compounds include transformation products, technical mixture impurities such as tris(chlorophenyl)methane (TCPM), the presumed TCPM metabolite tris(chlorophenyl)methanol (TCPMOH), and structurally related compounds with unknown sources, such as hexa- to octachlorinated diphenylethene. To investigate impurities in pesticide mixtures as possible sources of these compounds, we analyzed technical DDT, the primary source of historical contamination in the region, and technical Dicofol, a current use pesticide that contains DDT-related compounds. The technical mixtures contained only 33% of the compounds identified in the blubber, suggesting that transformation products contribute to the majority of the load of DDT-related contaminants in these sentinels of ocean health. Quantitative analysis revealed that TCPM was the second most abundant compound class detected in the blubber, following DDE, and TCPMOH loads were greater than DDT. QSPR estimates verified 4,4',4″-TCPM and 4,4'4,″-TCPMOH are persistent and bioaccumulative.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.