ArticleApplied and environmental microbiology2016
Effects of In-Feed Chlortetracycline Prophylaxis in Beef Cattle on Animal Health and Antimicrobial-Resistant Escherichia coli.
Article in Applied and environmental microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Population dynamics of enteric Salmonella in response to antimicrobial use in beef feedlot cattle.Scientific reports · 2017Trial
- Antimicrobial prescribing guidelines for feedlot cattle.Australian veterinary journal · 2026Article
- Interventions Targeting the Beef Feedlot Environment to Control Antimicrobial Resistance: A Mathematical Modelling Study.Zoonoses and public health · 2026Article
- Antimicrobials in Livestock Farming and Resistance: Public Health Implications.Antibiotics (Basel, Switzerland) · 2025Review
- Agriculturally Sourced Multidrug-ResistantPathogens (Basel, Switzerland) · 2025Article
- Editorial: Antimicrobial resistance in food-producing environments: a One Health approach.Frontiers in antibiotics · 2024Article
- Bovine Respiratory Disease: Conventional to Culture-Independent Approaches to Studying Antimicrobial Resistance in North America.Antibiotics (Basel, Switzerland) · 2022Review
- Decreasing the abundance of tetracycline-resistantVeterinary and animal science · 2022Article
- Effect of Protracted Free-Choice Chlortetracycline-Medicated Mineral for Anaplasmosis Control onMicroorganisms · 2021Article
- Removal of antimicrobial prophylaxis and its effect on swine carriage of antimicrobial-resistant coliforms.Science progress · 2021Article
- Stockpiling versus Composting: Effectiveness in Reducing Antibiotic-Resistant Bacteria and Resistance Genes in Beef Cattle Manure.Applied and environmental microbiology · 2021Article
- Prevalence and Risk Factors Associated With Antimicrobial Resistance in Bacteria Related to Bovine Respiratory Disease-A Broad Cross-Sectional Study of Beef Cattle at Entry Into Canadian Feedlots.Frontiers in veterinary science · 2021Article
- Antimicrobial Resistance inFrontiers in microbiology · 2021Article
- Prevalence, Risk Factors, and Antimicrobial Resistance Profile of Respiratory Pathogens Isolated From Suckling Beef Calves to Reprocessing at the Feedlot: A Longitudinal Study.Frontiers in veterinary science · 2021Article
- Influence of therapeutic use of feedgrade tetracyclines in combination with tulathromycin metaphylaxis on animal health and performance of Holstein steer calves.Translational animal science · 2019Article
- Quantitative dynamics of Salmonella and E. coli in feces of feedlot cattle treated with ceftiofur and chlortetracycline.PloS one · 2019Article
- Selection of Multidrug-Resistant Bacteria in Medicated Animal Feeds.Frontiers in microbiology · 2019Article
- Persistence of antibiotic resistance genes in beef cattle backgrounding environment over two years after cessation of operation.PloS one · 2019Article
- Effects of intermittent feeding of tylosin phosphate during the finishing period on feedlot performance, carcass characteristics, antimicrobial resistance, and incidence and severity of liver abscesses in steers.Journal of animal science · 2018Article
- Impact of "Raised without Antibiotics" Beef Cattle Production Practices on Occurrences of Antimicrobial Resistance.Applied and environmental microbiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Concerns have been raised that in-feed chlortetracycline (CTC) may increase antimicrobial resistance (AMR), specifically tetracycline-resistant (TET IMPORTANCE: The occurrence of human bacterial infections resistant to antimicrobial therapy has been increasing. It has been postulated that antimicrobial resistance was inevitable, but the life span of the antimicrobial era has been prematurely compromised due to the misuse of antimicrobials in clinical and agricultural practices. Direct evidence relating the use of antimicrobials in livestock production to diminished human health outcomes due to antimicrobial resistance is lacking, and the U.S. Food and Drug Administration has taken an approach to maximize therapeutic efficacy and minimize the selection of resistant microorganisms through judicious use of antimicrobials. This study demonstrated that prophylactic in-feed treatment of chlortetracycline administered for 5 days to calves entering feedlots is judicious, as this therapy reduced animal morbidity, reduced the use of antimicrobials more critical to human health, and had no long-term impact on the occurrence of antimicrobial-resistant E. coli.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.