Evidence map›Paper›PMID 27736769›Full record

ArticleAntimicrobial agents and chemotherapy2016

Occurrences and Characterization of Antibiotic-Resistant Bacteria and Genetic Determinants of Hospital Wastewater in a Tropical Country.

Thai-Hoang Le, Charmaine Ng, Hongjie Chen, Xin Zhu Yi, Tse Hsien Koh, Timothy Mark Sebastian Barkham, Zhi Zhou, Karina Yew-Hoong Gin

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  13. Complete genome sequence of carbapenem-resistant pathogenicMicrobiology resource announcements · 2024
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  19. A new class A beta-lactamase gene blaScientific reports · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Thai-Hoang LeNUS Environmental Research Institute (NERI), National University of Singapore, Singapore.
Charmaine NgNUS Environmental Research Institute (NERI), National University of Singapore, Singapore.
Hongjie ChenNUS Environmental Research Institute (NERI), National University of Singapore, Singapore.
Xin Zhu YiNUS Environmental Research Institute (NERI), National University of Singapore, Singapore.
Tse Hsien KohDepartment of Pathology, Singapore General Hospital, Singapore.
Timothy Mark Sebastian BarkhamDepartment of Laboratory Medicine, Tan Tock Seng Hospital, Singapore.
Zhi ZhouSchool of Civil Engineering and Division of Environmental and Ecological Engineering, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0003-1252-2626
Karina Yew-Hoong GinNUS Environmental Research Institute (NERI), National University of Singapore, Singapore ceeginyh@nus.edu.sg.
National University of Singapore · SGPurdue University West Lafayette · USSingapore General Hospital · SGTan Tock Seng Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wastewater discharged from clinical isolation and general wards at two hospitals in Singapore was examined to determine the emerging trends of antibiotic resistance (AR). We quantified the concentrations of 12 antibiotic compounds by analysis using liquid chromatography-tandem mass spectrometry (LC-MS/MS), antibiotic-resistant bacteria (ARB), the class 1 integrase gene (intI1), and 16 antibiotic resistance genes (ARGs) that confer resistance to 10 different clinically relevant antibiotics. A subset of 119 antibiotic-resistant isolates were phylogenetically classified and tested for the presence of ARGs encoding resistance to β-lactam antibiotics (bla

Indexed as

AmikacinAnti-Bacterial AgentsBacteriabeta-Lactamasesbeta-LactamsChromatography, LiquidCiprofloxacinDrug Resistance, MicrobialEscherichia coli ProteinsHospitalsHumansIntegrasesSingaporeTandem Mass SpectrometryTrimethoprim, Sulfamethoxazole Drug CombinationWastewaterAmikacinAnti-Bacterial Agentsbeta-lactamase CTX-M, E colibeta-lactamase KPC-1beta-lactamase NDM-1beta-lactamase PIT-2beta-Lactamasesbeta-LactamsCiprofloxacinEscherichia coli ProteinsIntegrasesintegron integrase IntI1Sul1 protein, E coliTrimethoprim, Sulfamethoxazole Drug CombinationWastewater

Identifiers

PMID27736769
PMCPMC5119029
OpenAlexW2530900398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.