Evidence map›Paper›PMID 27736036›Full record

ArticleJournal of diabetes investigation2017

Analysis of the association between glucose profiles and β-cell function for diabetic cardiovascular autonomic neuropathy in China.

Ping Fang, Jingcheng Dong, Fangfang Zeng, Zihui Tang

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02998944 (the Association Study of Constitution of Traditional Chinese Medicine and Common Diseases), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02998944 completednot on this map

the Association Study of Constitution of Traditional Chinese Medicine and Common Diseases

TypeobservationalSponsorShanghai Tongji Hospital, Tongji University School of MedicineRan2011 to 2016Enrolled3,748ConditionsHypertension, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease Moderate, Coronary Artery Disease
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Analysis of a Screening System for Diabetic Cardiovascular Autonomic Neuropathy in China.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ping FangDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jingcheng DongDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Fangfang ZengDepartment of Endocrinology and Metabolism, Fudan University Huashan Hospital, Shanghai, China.
Zihui TangDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Fudan University · CNHuashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionThe purpose of the present study was to investigate the severity of glucose profiles and β-cell function associated with diabetic cardiovascular autonomic neuropathy (DCAN) in a Chinese sample. MATERIALS AND

methodsA community-based, cross-sectional study to analyze the risk factors of DCAN was carried out with 455 individuals recruited from a Chinese population. The glucose profile risk score was calculated to identify the association between the severity of the glucose profiles and DCAN. The associations of the severity of the glucose profiles and β-cell function with DCAN were analyzed using multivariable logistic regression.

resultsUnivariate analysis showed that the glucose profiles and homeostatic model assessment of insulin resistance were significantly associated with the DCAN outcome, respectively. Multivariable logistic regression showed that significant associations exist between glucose profile indices and DCAN, after controlling for potential confounding factors (P < 0.01 for all) in both models. Multivariable logistic regression also showed that parameters of β-cell function were associated with the DCAN outcome in the category model (P < 0.1 for all). The glucose profile risk score was independently and significantly associated with the DCAN outcome after controlling for confounding factors (P < 0.001 and P for a trend <0.001).

conclusionsOur observations suggest that parameters of glucose profile indices and β-cell function are significantly and independently associated with DCAN, respectively. There was a tendency toward increased glucose profile risk score with increasing prevalence of DCAN.

Indexed as

AgedBlood GlucoseCardiovascular DiseasesChinaCross-Sectional StudiesDiabetic NeuropathiesFemaleHumansInsulin ResistanceInsulin-Secreting CellsMaleMiddle AgedRisk FactorsBlood GlucoseDiabetic cardiovascular autonomic neuropathyGlucose profileβ-Cell function

Identifiers

PMID27736036
PMCPMC5415463
OpenAlexW2531866103

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.