Evidence map›Paper›PMID 27735854›Full record

ArticleNutrients2016

Effects of Food Components That Activate TRPA1 Receptors on Mucosal Ion Transport in the Mouse Intestine.

Linda J Fothergill, Brid Callaghan, Leni R Rivera, TinaMarie Lieu, Daniel P Poole, Hyun-Jung Cho, David M Bravo, John B Furness

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. CaFrontiers in pharmacology · 2022
    Article
  9. Review
  10. Article
  11. Review
  12. The TRPA1 Agonist Cinnamaldehyde Induces the Secretion of HCOInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Remedia Sternutatoria over the Centuries: TRP Mediation.Molecules (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Linda J FothergillDepartment of Anatomy & Neuroscience, University of Melbourne, Parkville VIC 3010, Australia. l.fothergill@student.unimelb.edu.au.
Brid CallaghanDepartment of Anatomy & Neuroscience, University of Melbourne, Parkville VIC 3010, Australia. b.callaghan@unimelb.edu.ac.
Leni R RiveraDepartment of Anatomy & Neuroscience, University of Melbourne, Parkville VIC 3010, Australia. leni.rivera@deakin.edu.au.
TinaMarie LieuMonash Institute of Pharmaceutical Sciences, Monash University, Parkville VIC 3052, Australia. Tinamarie.lieu@monash.edu.
Daniel P PooleDepartment of Anatomy & Neuroscience, University of Melbourne, Parkville VIC 3010, Australia. Daniel.Poole@monash.edu.
Hyun-Jung ChoBiological Optical Microscopy Platform, University of Melbourne, Parkville VIC 3010, Australia. hcho@unimelb.edu.au.
David M BravoIn Vivo Animal Nutrition & Health, Talhouët, Saint-Nolff 56250, France. david.bravo@pancosma.ch.
John B FurnessDepartment of Anatomy & Neuroscience, University of Melbourne, Parkville VIC 3010, Australia. j.furness@unimelb.edu.au.
The University of Melbourne · AUDeakin University · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TRPA1 is a ligand-activated cation channel found in the intestine and other tissues. Components of food that stimulate TRPA1 receptors (phytonutrients) include allyl isothiocyanate, cinnamaldehyde and linalool, but these may also act at other receptors. Cells lining the intestinal mucosa are immunoreactive for TRPA1 and

Indexed as

AcroleinAcyclic MonoterpenesAnimalsCalciumColonDuodenumElectrophysiological PhenomenaEnterocytesFoodGene ExpressionHEK293 CellsHumansIntestinal MucosaIsothiocyanatesMaleMice2,3,4-tri-O-acetylarabinopyranosyl isothiocyanateAcroleinAcyclic MonoterpenesCalciumcinnamaldehydeIsothiocyanateslinaloolMonoterpenesPhytochemicalsSerotonin 5-HT3 Receptor AntagonistsTransient Receptor Potential ChannelsTRPA1 Cation ChannelTrpa1 protein, mouseenteroendocrine cellsintestinemicronutrientsserotonintransepithelial transporttransient receptor potential A1

Identifiers

PMID27735854
PMCPMC5084011
OpenAlexW2531647657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.