Evidence map›Paper›PMID 27735212›Full record

ArticleLeukemia & lymphoma2017

Upfront use of plerixafor and granulocyte-colony stimulating factor (GCSF) for stem cell mobilization in patients with multiple myeloma: efficacy and analysis of risk factors associated with poor stem cell collection efficiency.

Adebayo Ogunniyi, Mabel Rodriguez, Sean Devlin, Nelly Adel, Heather Landau, David J Chung, Nikoletta Lendvai, Alexander Lesokhin, Guenther Koehne, Sham Mailankody and 5 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01547806 (Mobilization and Collection of Autologous Stem Cell for Transplantation), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01547806 phase2completednot on this map

Mobilization and Collection of Autologous Stem Cell for Transplantation (ASCT) for Plasma Cell Myeloma (PCM)

TypeinterventionalSponsorNational Cancer Institute (NCI)Ran2012 to 2018Enrolled49ConditionsPlasma Cell Myeloma, Multiple MyelomaArmsFilgrastim, Plerixafor, Apheresis
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Mobilization Strategies in Myeloma Patients Intended for Autologous Hematopoietic Cell Transplantation.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Adebayo Ogunniyia Department of Pharmacy , Weill Cornell Medical College , New York , NY , USA.
Mabel Rodrigueza Department of Pharmacy , Weill Cornell Medical College , New York , NY , USA.
Sean Devlinb Department of Epidemiology and Biostatistics , Weill Cornell Medical College , New York , NY , USA.
Nelly Adela Department of Pharmacy , Weill Cornell Medical College , New York , NY , USA.
Heather Landauc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
David J Chungc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Nikoletta Lendvaic Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Alexander Lesokhinc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Guenther Koehnec Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Sham Mailankodyc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Neha Kordec Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Lilian Reichc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Ola Landgrenc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Sergio Giraltc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Hani Hassounc Department of Medicine , Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College , New York , NY , USA.
Cornell University · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
T LYMPHOCYTE SUBSET FUNCTION POST-TRANSPLANTATIONP01CA023766 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SCHEINBERG, DAVID A · 1985 to 2023
$59.0M
NCI NIH HHS P01 CA023766NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Plerixafor (P), an agent that selectively and reversibly binds to the chemokine receptor CXCR4, has been approved in combination with G-CSF (P + G-CSF) for stem cell (SC) mobilization in patients with multiple myeloma (MM). The goal of this study was to determine the SC collection success rate of P + G-CSF using a clinically relevant outcome defined as the ability to collect at least 5 × 10

Indexed as

Hematopoietic Stem Cell MobilizationAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBenzylaminesBiomarkersCyclamsFemaleGranulocyte Colony-Stimulating FactorHematopoietic Stem CellsHeterocyclic CompoundsHumansImmunoglobulin IsotypesMaleMiddle AgedBenzylaminesBiomarkersCyclamsGranulocyte Colony-Stimulating FactorHeterocyclic CompoundsImmunoglobulin IsotypesplerixaforefficiencymobilizationMultiple myelomaplerixaforrisk factorsstem cell

Identifiers

PMID27735212
PMCPMC5640442
OpenAlexW2531393228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.