Evidence map›Paper›PMID 27735094›Full record

ReviewJournal of the European Academy of Dermatology and Venereology : JEADV2016

Microbiome in healthy skin, update for dermatologists.

B Dréno, E Araviiskaia, E Berardesca, G Gontijo, M Sanchez Viera, L F Xiang, R Martin, T Bieber

Abstract readReview
In one paragraph

Review in Journal of the European Academy of Dermatology and Venereology : JEADV, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prevalence and Possible Role ofMediators of inflammation · 2018
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Development of Pharmabiotic Gel-Serums withGels (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Dysbiosis in the Pathogenesis of Atopic Dermatitis.The Journal of dermatology · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Cutibacterium acnes in lumbar spine, from skin to deep tissue. A colonization study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  20. Review

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B DrénoDepartment of Dermato-cancerology, Nantes University, Nantes, France.
E AraviiskaiaDepartment of Dermatology, First Pavlov State Medical University of St. Petersburg, St. Petersburg, Russia.
E BerardescaSan Gallicano Dermatological Institute, Rome, Italy.
G GontijoUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
M Sanchez VieraInstitute for Dermatology, Skin Health, Aging and Cancer, Madrid, Spain.
L F XiangDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
R MartinL'Oréal Research and Innovation, Tours, France.
T BieberDepartment of Dermatology and Allergy, University Medical Center, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is a complex barrier organ made of a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors which impact this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. Unlike the gut and stool microbiome which has been studied and described for many years, investigations on the skin or scalp microbiome only started recently. Researchers in microbiology and dermatology started using modern methods such as pyrosequencing assays of bacterial 16S rRNA genes to identify and characterize the different microorganisms present on the skin, to evaluate the bacterial diversity and their relative abundance and to understand how microbial diversity may contribute to skin health and dermatological conditions. This article aims to provide an overview on the knowledge about the skin microbiota, the microbiome and their importance in dermatology.

Indexed as

DermatologistsMicrobiotaBacteriaHumansRNA, Ribosomal, 16SSkinRNA, Ribosomal, 16S

Identifiers

PMID27735094
PMCPMC6084363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.