Evidence map›Paper›PMID 27734994›Full record

ArticleEuropean journal of histochemistry : EJH2016

NO-tryptophan: a new small molecule located in the rat brain.

A Mangas, J Yajeya, N González, S Duleu, M Geffard, R Coveñas

Open access · goldAbstract read
In one paragraph

Article in European journal of histochemistry : EJH, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Histochemistry today: Detection and location of single molecules.European journal of histochemistry : EJH · 2017
    Article
  3. Article
  4. Is there still room for novelty, in histochemical papers?European journal of histochemistry : EJH · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A MangasGemacbio - Institute for the Development of Research in Human Pathology and Therapeutic (IDRPHT) -University of Salamanca. amangas@gemacbio.com.
J Yajeya
N González
S Duleu
M Geffard
R Coveñas
Instituto de Estudios de Ciencias de la Salud de Castilla y León · ESUniversidad de Salamanca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A highly specific monoclonal antibody directed against nitric oxide-tryptophan (NO-W) with good affinity (10-9 M) and specificity was developed. In the rat brain, using an indirect immunoperoxidase technique, cell bodies containing NO-W were exclusively found in the intermediate and dorsal parts of the lateral septal nucleus. No immunoreactive fibres were found in the rat brain. This work reports the first visualization and the morphological characteristics of cell bodies containing NO-W in the mammalian brain. The restricted distribution of NO-W in the rat brain suggests that this molecule could be involved in specific physiological mechanisms.

Indexed as

AnimalsBrain ChemistryNitric OxideRatsRats, WistarSeptal NucleiTryptophanNitric OxideTryptophan

Identifiers

PMID27734994
PMCPMC5062636
OpenAlexW2526473693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.