Evidence map›Paper›PMID 27734570›Full record

ArticlePediatric blood & cancer2017

Socioeconomic status and global variations in the incidence of neuroblastoma: call for support of population-based cancer registries in low-middle-income countries.

Junne Kamihara, Clement Ma, Soad Linneth Fuentes Alabi, Claudia Garrido, A Lindsay Frazier, Carlos Rodriguez-Galindo, Manuela A Orjuela

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Prognostic factors of neuroblastoma in limited-resource settings.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
    Article
  4. Management of neuroblastoma in limited-resource settings.World journal of clinical oncology · 2020
    Article
  5. Correlation BetweenJournal of global oncology · 2019
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Novel Combination of Arsenic Trioxide (AsCancer genomics & proteomics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junne KamiharaDepartment of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Clement MaDepartment of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Soad Linneth Fuentes AlabiDepartment of Oncology, Benjamin Bloom National Children's Hospital, San Salvador, El Salvador.
Claudia GarridoNational Pediatric Oncology Unit, Francisco Marroquin Medical School, Guatemala City, Guatemala.
A Lindsay FrazierDepartment of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Carlos Rodriguez-GalindoSt. Jude Children's Research Hospital, Memphis, Tennessee.
Manuela A OrjuelaDepartment of Epidemiology and Pediatrics (Division of Oncology), Columbia University, New York, New York.

Funding

Methylation and mutations in RB1 and variants of synthetic folic acid metabolismR01CA192662 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ORJUELA, MANUELA A · 2015 to 2018
$1.5M
Unmetabolized folic acid and retinoblastoma.R21CA167833 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ORJUELA, MANUELA A · 2013 to 2014
$391k
NCI NIH HHS R01 CA192662NCI NIH HHS R21 CA167833
6 · The paper itself

Abstract

Global variations in the incidence of pediatric cancers have been described; however, the causes of such differences are not known. We investigated the relationship between the incidence of embryonal tumors and human development index on a global scale. Increasing incidence of neuroblastoma correlates significantly with an increasing index of human development, with greater incidence among countries with high socioeconomic development, in apparent contrast to the incidence of retinoblastoma. While more data are needed to corroborate this observation, our findings suggest new avenues for etiological research and serve as a call for support of population-based cancer registries in low-middle-income countries.

Indexed as

Human DevelopmentChild, PreschoolDeveloping CountriesFemaleGlobal HealthHumansIncidenceInfantInfant, NewbornMaleNeoplasms, Germ Cell and EmbryonalNeuroblastomaPovertyPrognosisRegistriesResidence Characteristicscancer registriesneuroblastomapediatric oncologysocioeconomic status

Identifiers

PMID27734570
PMCPMC5554414

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.