Evidence map›Paper›PMID 27734530›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2017

Time-Gated Detection of Cystathionine γ-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor.

Yao Yao, Chen Kong, Liang Yin, Atul D Jain, Kiira Ratia, Gregory R J Thatcher, Terry W Moore, Tom G Driver, Lawrence W Miller

Open access · greenAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yao YaoDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor Street, MC 111, Chicago, Illinois, 60607, USA.
Chen KongDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor Street, MC 111, Chicago, Illinois, 60607, USA.
Liang YinDepartment of Medicinal Chemistry and Pharmacognosy, UICentre for Drug Discovery, University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, 60612, USA.
Atul D JainDepartment of Medicinal Chemistry and Pharmacognosy, UICentre for Drug Discovery, University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, 60612, USA.
Kiira RatiaDepartment of Medicinal Chemistry and Pharmacognosy, UICentre for Drug Discovery, University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, 60612, USA.
Gregory R J ThatcherDepartment of Medicinal Chemistry and Pharmacognosy, UICentre for Drug Discovery, University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, 60612, USA.
Terry W MooreDepartment of Medicinal Chemistry and Pharmacognosy, UICentre for Drug Discovery, University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, 60612, USA.
Tom G DriverInstitute of Next Generation Matter Transformation, College of Chemical Engineering, Huaqiao University, 668 Jimei Blvd. Xiamen, Fujian, 361021, P. R. China.
Lawrence W MillerDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor Street, MC 111, Chicago, Illinois, 60607, USA.ORCID http://orcid.org/0000-0003-4501-9357
University of Illinois Chicago · USHuaqiao University · CN

Funding

Therapeutic Targeting of Carotid Body Chemoreflex for Sleep Disordered BreathingUH2HL123610 · NHLBI · UNIVERSITY OF CHICAGO · PI MCCORMICK, DAVID L., PETUKHOV, PAVEL A · 2014 to 2015
$3.3M
Targeted lanthanide contrast agents for in cellulo single molecule imagingR01GM081030 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MILLER, LAWRENCE · 2008 to 2018
$2.5M
NHLBI NIH HHS UH2 HL123610NIGMS NIH HHS R01 GM081030
6 · The paper itself

Abstract

Herein, we report the design, synthesis, and characterization of a lanthanide

Indexed as

Luminescent MeasurementsCystathionine gamma-LyaseEuropiumHigh-Throughput Screening AssaysHydrogen SulfideLanthanoid Series ElementsLuminescent AgentsMagnetic Resonance SpectroscopyCystathionine gamma-LyaseEuropiumHydrogen SulfideLanthanoid Series ElementsLuminescent Agentshigh-throughput screeninghydrogen sulfidelanthanidesluminescencesensors

Identifiers

PMID27734530
PMCPMC5250566
OpenAlexW2530235756

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.