Evidence map›Paper›PMID 27734519›Full record

ArticleMagnetic resonance in medicine2017

A hybrid multibreath wash-in wash-out lung function quantification scheme in human subjects using hyperpolarized

Hooman Hamedani, Stephen Kadlecek, Yi Xin, Sarmad Siddiqui, Heather Gatens, Joseph Naji, Masaru Ishii, Maurizio Cereda, Milton Rossman, Rahim Rizi

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. HyperpolarizedMagnetic resonance in medicine · 2022
    Review
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Multibreath HyperpolarizedAcademic radiology · 2019
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hooman HamedaniDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Stephen KadlecekDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yi XinDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sarmad SiddiquiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Heather GatensDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joseph NajiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Masaru IshiiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Maurizio CeredaDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Milton RossmanPulmonary, Allergy and Critical Care Division, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rahim RiziDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USJohns Hopkins University · US

Funding

Quantitative Structural and Functional Imaging of the LungR01HL089064 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2008 to 2013
$3.1M
Imaging-based characterization of the COPDGene cohortR01HL127969 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2015 to 2018
$2.8M
NHLBI NIH HHS R01 HL089064NHLBI NIH HHS R01 HL127969
6 · The paper itself

Abstract

purposeTo present a method for simultaneous acquisition of alveolar oxygen tension (P

methodAn imaging scheme was designed with a series of identical normoxic HP gas wash-in breaths to measure ADC, SV, P

resultsThe overall whole lung ADC, SV, P

conclusionHigh-resolution, nearly coregistered and quantitative measures of lung function and structure were obtained with less than 1 L of HP gas. This hybrid multibreath technique produced measures of lung function that revealed clear differences among the cohorts and subjects and were confirmed by correlations with global lung measurements. Magn Reson Med 78:611-624, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

AdultBreath HoldingFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedOxygenPulmonary AlveoliPulmonary Disease, Chronic ObstructiveRespirationTritiumOxygenTritiumalveolar oxygen tensionhybrid (simultaneous) imaginghyperpolarized multibreath imagingoxygen uptakespecific ventilation

Identifiers

PMID27734519
PMCPMC5391315
OpenAlexW2535688999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.