ArticleCerebellum (London, England)2017
Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia.
Article in Cerebellum (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
131 citing papers in PubMed, 2 syntheses or guidelines pooled it, 234 citations in OpenAlex.
- A Systematic Review of Cognition in Cervical Dystonia.Neuropsychology review · 2024Pooled it
- The Effect of Cerebellar rTMS on Modulating Motor Dysfunction in Neurological Disorders: a Systematic Review.Cerebellum (London, England) · 2023Pooled it
- Differential effects of propranolol on head and upper limb tremor in patients with essential tremor and dystonia.Journal of neurology · 2018Trial
- Generalized Dystonia in Fahr's Syndrome Secondary to Idiopathic Hypoparathyroidism: Improvement After Metabolic Correction.Journal of clinical neurology (Seoul, Korea) · 2026Article
- Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026Review
- "Tapping" into neural inhibition in focal hand dystonia: an evaluation of a finger-tapping task using TMS and fMRI.Journal of neurology · 2026Article
- Validation of a torsinA cerebellar knockdown model of DYT1 dystonia.Dystonia (Lausanne, Switzerland) · 2026Article
- Altered motor network dynamics in myoclonus-dystonia.Brain communications · 2026Article
- Shared and distinct dynamic brain activity and functional connectivity variability in patients with isolated craniocervical dystonia.Brain communications · 2026Article
- Tremor pathophysiology.Clinical parkinsonism & related disorders · 2026Review
- Pathophysiology of dystonia: Through the lens of Mark Hallett.Clinical parkinsonism & related disorders · 2026Review
- The cerebellum in dystonia: key player or background support?Arquivos de neuro-psiquiatria · 2025Review
- Article
- More than a Movement Disorder: Non-Motor Features and Future Directions in Dystonia Research.Brain sciences · 2025Review
- Somato-Cognitive Action Network in Focal Dystonia.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Neuroscience of human ventral lateral thalamic nucleus related to movement and movement disorders.Journal of neurophysiology · 2025Review
- Posterior Inferior Cerebellar Artery Infarct Associated With Cervical Dystonia: A Case Report.Cureus · 2025Article
- Structure-function association of the cerebellar motor network is altered in isolated cervical dystonia.Journal of neurology · 2025Article
- Multivariate Pattern Analysis of fMRI Reveals Striato-Cortical Network Changes in Myoclonus-Dystonia.European journal of neurology · 2025Article
- Thalamic deep brain stimulation improves movement in a cerebellar model of lesion-based status dystonicus.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 15 institutions in 3 countries.
Funding
Abstract
A role for the cerebellum in causing ataxia, a disorder characterized by uncoordinated movement, is widely accepted. Recent work has suggested that alterations in activity, connectivity, and structure of the cerebellum are also associated with dystonia, a neurological disorder characterized by abnormal and sustained muscle contractions often leading to abnormal maintained postures. In this manuscript, the authors discuss their views on how the cerebellum may play a role in dystonia. The following topics are discussed: The relationships between neuronal/network dysfunctions and motor abnormalities in rodent models of dystonia. Data about brain structure, cerebellar metabolism, cerebellar connections, and noninvasive cerebellar stimulation that support (or not) a role for the cerebellum in human dystonia. Connections between the cerebellum and motor cortical and sub-cortical structures that could support a role for the cerebellum in dystonia. Overall points of consensus include: Neuronal dysfunction originating in the cerebellum can drive dystonic movements in rodent model systems. Imaging and neurophysiological studies in humans suggest that the cerebellum plays a role in the pathophysiology of dystonia, but do not provide conclusive evidence that the cerebellum is the primary or sole neuroanatomical site of origin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.