ArticleHeart and vessels2017
Relationships of left ventricular strain and strain rate to wall stress and their afterload dependency.
Article in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Left ventricular deformation predicts major adverse cardiac events following acute myocardial infarction independently of afterload and ventricular-arterial coupling.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Strain-based characterization of atrioventricular and left atrial remodelling in rat models of heart failure with preserved ejection fraction.Experimental physiology · 2026Article
- Application of VVI layered strain technology to analyze changes in left ventricular myocardial motion in patients with uremia.PloS one · 2026Article
- Exercise-induced out-of-proportion increase in afterload and impaired right ventricular contractile reserve in HFpEF.ESC heart failure · 2025Article
- Correlation between myocardial work and disease activity in rheumatoid arthritis patients with preserved left ventricular ejection fraction: a retrospective study based on non-invasive pressure-strain loop：.Clinical rheumatology · 2025Article
- Diverse distribution patterns of segmental longitudinal strain are associated with different clinical features and outcomes in dilated cardiomyopathy.Journal of echocardiography · 2024Article
- Myocardial Work Index in Professional Football Players: A Novel Method for Assessment of Cardiac Adaptation.Journal of clinical medicine · 2023Article
- First-Phase Left Ventricular Ejection Fraction as an Early Sign of Left Ventricular Dysfunction in Patients with Stable Coronary Artery Disease.Journal of clinical medicine · 2023Article
- Comparison of two ellipsoidal models for the estimation of left ventricular end-systolic stress in patients with significant coronary artery disease.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Echocardiographic Normal Reference Ranges for Non-invasive Myocardial Work Parameters in Pediatric Age: Results From an International Multi-Center Study.Frontiers in cardiovascular medicine · 2022Article
- Determinants of the Volumetric Markers of Left Atrial Contraction Function in Coronary Artery Disease: A Cross-sectional Study.Journal of cardiovascular imaging · 2022Article
- DeepStrain Evidence of Asymptomatic Left Ventricular Diastolic and Systolic Dysfunction in Young Adults With Cardiac Risk Factors.Frontiers in cardiovascular medicine · 2022Article
- Clinical Assessment of Ventricular Wall Stress in Understanding Compensatory Hypertrophic Response and Maladaptive Ventricular Remodeling.Journal of cardiovascular development and disease · 2021Review
- Prediction of Significant Coronary Artery Disease Through Advanced Echocardiography: Role of Non-invasive Myocardial Work.Frontiers in cardiovascular medicine · 2021Article
- Dynamic Handgrip Exercise: Feasibility and Physiologic Stress Response of a Potential Needle-Free Cardiac Magnetic Resonance Stress Test.Frontiers in cardiovascular medicine · 2021Article
- Effects of Different Systolic Blood Pressure Targets on Myocardial Function: A One-Year Follow-Up in Geriatric Hypertension.International journal of general medicine · 2021Article
- Distribution of myocardial work in arterial hypertension: insights from non-invasive left ventricular pressure-strain relations.The international journal of cardiovascular imaging · 2021Article
- Regional heterogeneity of afterload sensitivity in myocardial strain.Journal of medical ultrasonics (2001) · 2020Article
- Myocardial Work Index: A Novel Method for Assessment of Myocardial Function in South Asian Recreational Athletes.Journal of patient-centered research and reviews · 2020Article
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Abstract
Whether and how left ventricular (LV) strain and strain rate correlate with wall stress is not known. Furthermore, it is not determined whether strain or strain rate is less dependent on the afterload. In 41 healthy young adults, LV global peak strain and systolic peak strain rate in the longitudinal direction (LS and LSR, respectively) and circumferential direction (CS and CSR, respectively) were measured layer-specifically using speckle tracking echocardiography (STE) before and during a handgrip exercise. Among all the points before and during the exercise, all the STE parameters significantly correlated linearly with wall stress (LS: r = -0.53, p < 0.01, LSR: r = -0.28, p < 0.05, CS in the inner layer: r = -0.72, p < 0.01, CSR in the inner layer: r = -0.47, p < 0.01). Strain more strongly correlated with wall stress than strain rate (r = -0.53 for LS vs. r = -0.28 for LSR, p < 0.05; r = -0.72 for CS vs. r = -0.47 for CSR in the inner layer, p < 0.05), whereas the interobserver variability was similar between strain and strain rate (longitudinal 6.2 vs. 5.2 %, inner circumferential 4.8 vs. 4.7 %, mid-circumferential 7.9 vs. 6.9 %, outer circumferential 10.4 vs. 9.7 %), indicating that the differences in correlation coefficients reflect those in afterload dependency. It was thus concluded that LV strain and strain rate linearly and inversely correlated with wall stress in the longitudinal and circumferential directions, and strain more strongly depended on afterload than did strain rate. Myocardial shortening should be evaluated based on the relationships between these parameters and wall stress.
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