ArticleBiomicrofluidics2016
Characterization of thermoplastic microfiltration chip for the separation of blood plasma from human blood.
Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- 3D Printed Devices for the Separation of Blood Plasma from Capillary Samples.Micromachines · 2024Article
- Particle Size-Dependent Component Separation Using Serially Arrayed Micro-Chambers.Micromachines · 2023Article
- Microfabrication of Nonplanar Polymeric Microfluidics.Micromachines · 2018Article
- Network simulation-based optimization of centrifugo-pneumatic blood plasma separation.Biomicrofluidics · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we developed a fully thermoplastic microfiltration chip for the separation of blood plasma from human blood. Spiral microchannels were manufactured on a PMMA substrate using a micromilling machine, and a commercial polycarbonate membrane was bonded between two thermoplastic substrates. To achieve an excellent bonding between the commercial membrane and the thermoplastic substrates, we used a two-step injection and curing procedure of UV adhesive into a ring-shaped structure around the microchannel to efficiently prevent leakage during blood filtration. We performed multiple filtration experiments using human blood to compare the influence of three factors on separation efficiency: hematocrit level (40%, 23.2%, and 10.9%), membrane pore size (5
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Registered trials
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