Evidence map›Paper›PMID 27733866›Full record

ArticleChinese medicine2016

Inhibitory effect of

Yao Fong, Chia-Chun Tang, Huei-Ting Hu, Hsin-Yu Fang, Bing-Hung Chen, Chang-Yi Wu, Shyng-Shiou Yuan, Hui-Min David Wang, Yen-Chun Chen, Yen-Ni Teng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Chinese medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 53 citations in OpenAlex.

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    Review
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  17. Review
  18. Immunomodulatory and Anticancer Activities ofPlants (Basel, Switzerland) · 2021
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  20. Ethanol extract ofChinese medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Yao Fong *Department of Thoracic Surgery, Chi-Mei Medical Center, Tainan, 710 Taiwan.
Chia-Chun Tang *Division of Chest, Ten Chan General Hospital, Chung-Li, 320 Taiwan, ROC.
Huei-Ting HuDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung, 807 Taiwan.
Hsin-Yu FangDepartment of Food Nutrition, Chung-Hwa University of Medical Technology, Tainan, 701 Taiwan.
Bing-Hung ChenDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung, 807 Taiwan.
Chang-Yi WuDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung, 807 Taiwan.
Shyng-Shiou YuanTranslational Research Center, Kaohsiung Medical University Hospital, Kaohsiung, 807 Taiwan.
Hui-Min David WangGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402 Taiwan.
Yen-Chun ChenDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung, 807 Taiwan.
Yen-Ni TengDepartment of Biological Sciences and Technology, National University of Tainan, Tainan, 700 Taiwan.
Chien-Chih ChiuDepartment of Biotechnology, Kaohsiung Medical University, Kaohsiung, 807 Taiwan.
Kaohsiung Medical University · TWChi Mei Medical Center · TWChung Hwa University of Medical Technology · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWNational Chung Hsing University · TWNational Sun Yat-sen University · TWNational University of Tainan · TWTen Chen Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe 2,2-diphenyl-1-picrylhydrazyl assay was used to determine free radical scavenging capability. Assessment of intracellular reactive oxygen species (ROS) was evaluated using oxidized 2',7'-dichlorofluorescin diacetate and dihydroethidium staining. Trypan blue exclusion, colony formation, and anchorage-independent growth assays were used to determine cellular proliferation. Annexin V staining assay was used to assess cellular apoptosis by flow cytometry. Wound healing and Boyden's well assays were used to detect the migration and invasion of cells. Gelatin zymography was used to detect matrix metalloproteinase (MMP-2 and MMP-9) activity. Western blotting was used to detect expression levels of various signaling pathway proteins.

resultsDPPH assay results indicated that

conclusionVarious concentrations (0.06-0.6 mM) of

Identifiers

PMID27733866
PMCPMC5045596
OpenAlexW2525022454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.