ArticleCancer cell international2016
Cytologic studies of the fallopian tube in patients undergoing salpingo-oophorectomy.
Article in Cancer cell international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Early Detection and Prevention of Ovarian Cancer.Cancers · 2025Review
- CytoSaLPs score: a promising new tool for the detection and screening of extrauterine high grade serous carcinoma.BMC cancer · 2023Article
- Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution.BMC medicine · 2022Article
- Cytologic studies ofCytoJournal · 2020Article
- Novel Approaches to Ovarian Cancer Screening.Current oncology reports · 2019Review
- Cytomorphologic and molecular analyses of fallopian tube fimbrial brushings for diagnosis of serous tubal intraepithelial carcinoma.Cancer cytopathology · 2019Article
- Tubal Origin of "Ovarian" Low-Grade Serous Carcinoma: A Gene Expression Profile Study.Journal of oncology · 2019Article
- Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection.Journal of visualized experiments : JoVE · 2017Article
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5 authors.
Funding
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Abstract
backgroundMounting evidence suggests the fallopian tube as the origin for ovarian high grade serous carcinoma (HGSC). We attempted to identify the tubal cytological features that allow us to distinguish malignant from benign conditions.
methodsTubal specimens (n = 56) were collected from patients who underwent bilateral salpingo-oophorectomy (BSO) due to various clinical indications. A standard procedure to collect fallopian tube brushings from freshly received surgical specimens was developed. Cytological diagnoses were classified into three categories: benign, atypical, and suspicious for malignancy/malignant. Cytological variables of individual cells and epithelia were subjected to statistical analysis. The fallopian tube histology was used as diagnostic reference for confirmation of cytology diagnosis.
resultsAmong the 56 fallopian tube specimens, 2 (3.7 %) showed inadequate cellularity preventing further evaluation, 11 (20.4 %) were diagnosed as malignant or suspicious of malignancy, 7 were atypical, and 36 were benign. The presence of three dimensional clusters (
conclusionsTubal cytology may be useful for ovarian cancer screening and early detection.
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